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TP53 BRCA1 CRISPR single-cell cancer

Gaildrat(Pascaline),Krieger(Sophie),Di Gia... J Med Genet 2013-03-14

...BRCA2. We studied the effect on splicing of eight exon 7 VUS, selected from the French UMD-BRCA2 mutation database.,We p...

Beltran(Himisha),Yelensky(Roman),Frampton(... Eur Urol 2013-09-24

...BRCA2) loss (12%) and ataxia telangiectasia mutated gene (ATM) mutations (8%); these alterations are potentially targeta...

Oplustilova(Lenka),Wolanin(Kamila),Mistrik... Cell Cycle 2013-03-01

...BRCA2-defective tumors (hence defective in DNA repair by homologous recombination, HR) to inhibitors of the poly(ADP-rib...

Nagel(Anja C),Fischer(Patrick),Szawinski(J... J Cell Sci 2013-07-16

...BRCA2. These two proteins are components of the 9-1-1 complex, which is involved in sensing DSBs and in activating meiot...

Bambury(Richard M),Gallagher(David J) BJU Int 2013-02-05

...BRCA2 and HOXB13 can affect prostate cancer incidence and/or clinical behaviour. Genome wide association studies (GWAS) ...

Reitsma(Welmoed),de Bock(Geertruida H),Oos... Eur J Cancer 2013-02-27

...BRCA2-carriers and 57 BRCA-negative women at a median age of 44.0 years. Four occult invasive cancers were detected in B...

Chan(Maurice),Ji(Shen Mo),Yeo(Zhen Xuan),G... J Mol Diagn 2013-02-28

...BRCA2 genes, generated using a PCR-based, multiplexed NGS approach using the SOLiD 4 (n = 24) and Ion Torrent PGM (n = 2...

Novaković(Srdjan),Milatović(Maša),Cerkovni... Int J Oncol 2013-03-22

...BRCA2 genes. Three novel mutations were detected: one in BRCA1 - c.1193C>A (p.Ser398*) and two in BRCA2 - c....

Buisson(Rémi),Masson(Jean-Yves) Nucleic Acids Res 2013-01-24

...BRCA2 anchorage to nuclear structures and for homologous recombinational repair of DNA double-strand breaks. Here, we re...

Wang(Qi),Liu(Hongrui),Liu(Tingting),Shu(Sh... Anticancer Agents Med Chem 2013-08-05

...BRCA2 RNA interference in PanIN cell isolated from mice with oncogenic KrasG12D. Our data showed that silencing of BRCA2...

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