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TP53 BRCA1 CRISPR single-cell cancer

Nelson-Moseke(Anna C),Jeter(Joanne M),Cui(... Fam Cancer 2013-07-18

...BRCA2 mutations appear in our clinic population. The increased proportion of probands carrying deleterious BRCA2 mutatio...

Werner(Haim),Bruchim(Ilan) Lancet Oncol 2013-02-04

...BRCA2 have an important role in the development of hereditary and sporadic breast and ovarian cancer. Recent evidence su...

Mazzola(Emanuele),Cheng(Su-Chun),Parmigian... Breast Cancer Res Treat 2013-05-27

...BRCA2 deleterious mutation. We jointly re-analyze the SEER9 database and a previous study by Claus et al. (JAMA 293:964-...

Cott Chubiz(Jessica E),Lee(Janie M),Gilmor... Cancer 2013-04-23

...BRCA2 mutation carriers. Three dual-modality strategies were compared with digital mammography (DM) alone: 1) DM and MRI...

Yuan(Jing),Strack(Peter R),Toniatti(Carlo)... Anal Biochem 2013-08-14

...BRCA2 decreased HR activity in cells, whereas gene restoration induced activity 8-fold. HR activity was also reflective ...

Chun(Jarin),Buechelmaier(Erika S),Powell(S... Mol Cell Biol 2013-02-21

...BRCA2 and synthetically lethal with Rad52. We conclude that human Rad51 paralogs facilitate BRCA2-Rad51-dependent homolo...

Rinner(Beate),Gallè(Birgit),Trajanoski(Sla... BMC Genomics 2013-04-23

...BRCA2, CTNNB1, ERCC5, HNF1A, KIT, MLL, RB1, ROS1, SMAD4, and TP53. All mutations were confirmed in the patients' lymph n...

Janavičius(Ramūnas) EPMA J 2013-01-01

Detection of mutations in hereditary breast and ovarian cancer-related BRCA1 and BRCA2 genes is an effective method of c...

Meiser(Bettina),Price(Melanie A),Butow(Phy... Fam Cancer 2013-07-18

...BRCA2 mutation carrier or family history including at least one first- or second-degree relative with ovarian or fallopi...

Solomon(Sheila),Das(Siddhartha),Brand(Rand... Cancer J 2013-08-08

...BRCA2, PALB2, ATM, CDKN2A, APC, MLH1, MSH2, MSH6, PMS2, PRSS1, and STK11. Recognition of members of high-risk families i...

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