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Genotype in BRCA-associated breast cancers.

Meric-Bernstam(Funda),Gutierrez-Barrera(Ange… Breast J 2013-06-24

...BRCA2-associated cancers (p < 0.0001), there was no difference in the tumor characteristics among BRCA1 or BRCA2-associa...

Contribution of the PALB2 c.2323C&gt;T [p.Q775X] founder mutation in well-defined …

Tischkowitz(Marc),Sabbaghian(Nelly),Hamel(Na… BMC Med Genet 2013-03-14

...BRCA2 mutations reported in the French Canadian population and in 491 women of French Canadian descent who had invasive ...

Mutation screening of the BRCA1 gene in early onset and familial breast/ovarian…

Laraqui(Abdelilah),Uhrhammer(Nancy),Lahlou-A… Int J Med Sci 2013-07-12

...BRCA2 in BC is also under study.

Molecular cytogenetics as a clinical test for prognostic and predictive biomark…

Gunn(Shelly),Reveles(Xavier),Weldon(Korrie),… J Ovarian Res 2013-03-20

...BRCA2 gene deletions. Bi-allelic PTEN gene deletion was detected in one patient's tumor.,Clinical genomic profiling of o...

Optimal age to start preventive measures in women with BRCA1/2 mutations or hig…

Tilanus-Linthorst(Madeleine M A),Lingsma(Hes… Int J Cancer 2013-06-11

...BRCA2 and 244 high-risk participants of the Dutch MRI-SCreening study. The within- and between-family variance in the re...

Reproductive decision-making in young female carriers of a BRCA mutation.

Donnelly(L S),Watson(M),Moynihan(C),Bancroft… Hum Reprod 2013-09-26

...BRCA2 gene mutation while childless.,Analysis revealed four central themes: (i) the impact of cancer on reproductive dec...

Effect of the expression of BRCA2 on spontaneous homologous recombination and D…

Spugnesi(Laura),Balia(Cristina),Collavoli(An… Mutagenesis 2013-08-16

...BRCA2 missense variants. Therefore, we expressed the wild-type BRCA2 in yeast and determined the effect of BRCA2 on yeas...

Familial prostate cancer: the damage done and lessons learnt.

Taherian(Nassim),Hamel(Nancy),Bégin(Louis R)… Nat Rev Urol 2013-10-29

...BRCA2 genes, histopathological review of tumour tissue from family members, examination of loss of heterozygosity at the...

Low prevalence of SLX4 loss-of-function mutations in non-BRCA1/2 breast and/or …

de Garibay(Gorka Ruiz),Díaz(Avellaneda),Gavi… Eur J Hum Genet 2013-10-29

...BRCA2 multiple-case breast and/or ovarian cancer families (non-BRCA1/2 families) from Spain. We detected one unequivocal...

Activation of Evi1 inhibits cell cycle progression and differentiation of hemat…

Kustikova(O S),Schwarzer(A),Stahlhut(M),Brug… Leukemia 2013-07-19

...Brca2, Rad51). Cell cycle analysis demonstrated EVI1's anti-proliferative effect to be strictly dose-dependent with accu...

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