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TP53 BRCA1 CRISPR single-cell cancer

Stevens(Kristen N),Wang(Xianshu),Frederick... Breast Cancer Res Treat 2013-05-23

...BRCA2 mutation carriers (HR = 1.09, 95 % CI 0.96-1.24, p = 0.18). No association with ovarian cancer risk for BRCA1 or B...

Bjørnslett(Merete),Knappskog(Stian),Lønnin... BMC Cancer 2013-05-23

...BRCA2; n = 60) were tested for the MDM2 polymorphisms. Results were compared to healthy controls (n = 2,465).,The SNP309...

Willems-Jones(Amber),Kavanagh(Liam),Cloust... BJU Int 2013-02-05

...BRCA2. An earlier study by the Kathleen Cuningham Consortium for Research into Familial Breast Cancer showed that BRCA2 ...

Pal(Tuya),Vadaparampil(Susan T) Cancer Control 2013-05-09

...BRCA2. Specifically, the value of genetic counseling and testing for HBOC across the cancer prevention and control conti...

Yeo(Zhen Xuan),Chan(Maurice),Yap(Yoon Sim)... PLoS One 2013-02-28

...BRCA2 genes from six germline samples was done. Three commonly used variant detection tools, SAMtools, Dindel, and GATK'...

DiMillo(J),Samson(A),Thériault(A),Lowry(S)... Psychol Health Med 2013-08-05

...BRCA2 genetic mutation have an up to 80% lifetime risk of developing breast cancer. It is especially important to unders...

de Bruin(Monique A),Kwong(Ava),Goldstein(B... Fam Cancer 2013-05-03

The prevalence and penetrance of BRCA1 and BRCA2 (BRCA1/2) mutations may differ between Asians and whites. We investigat...

Pennington(Kathryn P),Walsh(Tom),Lee(Ming)... Cancer 2013-02-20

...BRCA2, the DNA mismatch repair genes (MLH1 [mutL homolog 1], MSH2 [mutS homolog 2], MSH6, PMS2 [postmeiotic segregation ...

Maxwell(Kara N),Domchek(Susan M) Nat Rev Clin Oncol 2013-01-24

...BRCA2 have markedly elevated risks of breast and ovarian cancer and the identification of these germline mutations has l...

Clark(Caroline C),Weitzel(Jeffrey N),O'Con... Mol Cancer Ther 2013-02-07

Individuals with an inherited BRCA1 or BRCA2 mutation have an elevated risk of developing breast cancer. The resulting t...

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