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Prognostically relevant gene signatures of high-grade serous ovarian carcinom...

Verhaak(Roel G W),Tamayo(Pablo),Yang(Ji-Ye... J Clin Invest 2013-03-11

...BRCA2 mutation status, residual disease after surgery, and disease stage further optimized outcome classification. Ovari...

Implications of BRCA1 and BRCA2 mutations for the efficacy of paclitaxel mono...

Tan(David S P),Yap(Timothy A),Hutka(Margar... Eur J Cancer 2013-05-28

...BRCA2 (BRCA1/2)-mutated ovarian cancers (BMOC) are exquisitely sensitive to platinum-salts, but resistant to microtubule...

Risk of asynchronous contralateral breast cancer in noncarriers of BRCA1 and ...

Reiner(Anne S),John(Esther M),Brooks(Jenni... J Clin Oncol 2013-03-11

...BRCA2 mutations.,From our population-based case-control study comparing women with CBC to women with unilateral breast c...

BRCA-associated pancreatic cancer: the evolving management.

Leung(Keith),Saif(Muhammad Wasif) JOP 2013-09-12

...BRCA2-associated pancreatic cancer treated with the poly-(ADP-ribose) polymerase (PARP) inhibitor ABT-888 (veliparib). W...

Comprehensive analysis of BRCA1, BRCA2 and TP53 germline mutation and tumor c...

Carraro(Dirce Maria),Koike Folgueira(Maria... PLoS One 2013-08-27

Germline mutations in BRCA1, BRCA2 and TP53 genes have been identified as one of the most important disease-causing issu...

Predicting high risk disease using serum and DNA biomarkers.

Vesprini(Danny),Liu(Stanley),Nam(Robert) Curr Opin Urol 2013-09-24

...BRCA2, Phosphatase and tensin homolog, cellular myelocytomatosis oncogene and NKX3.1 may predict for aggressive high gra...

Design, synthesis, and biological evaluation of a series of benzo[de][1,7]nap...

Ye(Na),Chen(Chuan-Huizi),Chen(Tiantian),So... J Med Chem 2013-06-11

...BRCA2-deficient cells. Significant potentiation on the cytotoxicity of Temozolomide was also observed. The unique struct...

Prevalence of BRCA1 mutations in familial and sporadic greek ovarian cancer c...

Stavropoulou(Alexandra V),Fostira(Florenti... PLoS One 2013-12-27

Germline mutations in the BRCA1 and BRCA2 genes contribute to approximately 18% of hereditary ovarian cancers conferring...

The incidence of endometrial cancer in women with BRCA1 and BRCA2 mutations: ...

Segev(Yakir),Iqbal(Javaid),Lubinski(Jan),G... Gynecol Oncol 2013-08-19

...BRCA2 gene.,We followed 4456 women with a BRCA1 or a BRCA2 mutation for incident cases of endometrial cancer. The incide...

DNA copy number profiling reveals extensive genomic loss in hereditary BRCA1 ...

Kamieniak(M M),Muñoz-Repeto(I),Rico(D),Oso... Br J Cancer 2013-07-15

...BRCA2 and 26 non-BRCA1/2) and 15 sporadic tumours in combination with supervised and unsupervised analysis was used to d...

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