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Baseline E(2) levels are higher in BRCA2 mutation carriers: a potential targe...

Kim(Jayeon),Oktay(Kutluk) Cancer Causes Control 2013-12-11

...BRCA2 mutation carriers, BRCA1 mutation carriers, and non-carriers, respectively, p value = 0.03). Women with BRCA2 muta...

Nonfamilial breast cancer subtypes.

Ringnér(Markus),Staaf(Johan),Jönsson(Göran... Methods Mol Biol 2013-07-29

...BRCA2-mutated tumors were significantly correlated to specific subtypes. In this chapter, we will review the current sta...

Impairment of BRCA1-related DNA double-strand break repair leads to ovarian a...

Titus(Shiny),Li(Fang),Stobezki(Robert),Aku... Sci Transl Med 2013-07-26

...BRCA2, declines in single mouse and human oocytes. In Brca1-deficient mice, reproductive capacity was impaired, primordi...

Whole exome sequencing suggests much of non-BRCA1/BRCA2 familial breast cance...

Gracia-Aznarez(Francisco Javier),Fernandez... PLoS One 2013-09-06

The identification of the two most prevalent susceptibility genes in breast cancer, BRCA1 and BRCA2, was the beginning o...

HIF-1α overexpression in ductal carcinoma in situ of the breast in BRCA1 and ...

van der Groep(Petra),van Diest(Paul J),Smo... PLoS One 2013-08-05

...BRCA2 and 77 non-BRCA mutation-related cases. HIF-1α expression was detected in 63% of BRCA1 and 62% of BRCA2 as compare...

Germline BRCA mutations are associated with higher risk of nodal involvement,...

Castro(Elena),Goh(Chee),Olmos(David),Saund... J Clin Oncol 2013-07-01

To analyze the baseline clinicopathologic characteristics of prostate tumors with germline BRCA1 and BRCA2 (BRCA1/2) mut...

PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene...

Chatterjee(Payel),Choudhary(Gaurav S),Shar... PLoS One 2013-09-23

...BRCA2 that impair homologous recombination. However, since many tumors, including prostate cancer (PCa) rarely have on s...

Genetic predisposition syndromes and their management.

Euhus(David M),Robinson(Linda) Surg Clin North Am 2013-04-22

...BRCA2, and TP53, more than a dozen breast cancer susceptibility genes have been identified. Recognizing affected individ...

Miscellaneous syndromes and their management: occult breast cancer, breast ca...

Colfry(Alfred John) Surg Clin North Am 2013-04-22

...BRCA2 mutations, as well as Klinefelter syndrome. Several retrospective trials of surgical therapy in stage IV breast ca...

A prospective investigation of predictive and modifiable risk factors for bre...

Guinan(Emer M),Hussey(Juliette),McGarrigle... BMC Cancer 2013-09-16

...BRCA2, the risk of developing breast or ovarian cancer is significantly increased. In recent years there has been increa...

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