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TP53 BRCA1 CRISPR single-cell cancer

Smetsers(Stephanie),Muter(Joanne),Bristow(... Fam Cancer 2013-04-23

...BRCA2, FANCJ/BRIP1, FANCN/PALB2, RAD51C/FANCO and link the FA pathway to inherited breast and ovarian cancer. We describ...

Maxwell(Kara N),Domchek(Susan M) Nat Rev Clin Oncol 2013-01-24

...BRCA2 have markedly elevated risks of breast and ovarian cancer and the identification of these germline mutations has l...

Watts(Kaaren J),Meiser(Bettina),Mitchell(G... BMC Cancer 2013-01-17

...BRCA2 mutation testing offered shortly after a breast cancer diagnosis to inform women's treatment choices - treatment-f...

Pennington(Kathryn P),Walsh(Tom),Lee(Ming)... Cancer 2013-02-20

...BRCA2, the DNA mismatch repair genes (MLH1 [mutL homolog 1], MSH2 [mutS homolog 2], MSH6, PMS2 [postmeiotic segregation ...

McMillen(Brian D),Aponte(Margarita M),Liu(... Mod Pathol 2013-06-06

...BRCA2 mutations are common and the hallmarks of high-grade serous ovarian carcinoma. We found that MIR182, a negative BR...

Clark(Caroline C),Weitzel(Jeffrey N),O'Con... Mol Cancer Ther 2013-02-07

Individuals with an inherited BRCA1 or BRCA2 mutation have an elevated risk of developing breast cancer. The resulting t...

Bayraktar(Soley),Glück(Stefan) Breast Cancer Res Treat 2013-01-04

...BRCA2 genes, and their differential chemosensitivity in both the preclinical and clinical settings. The optimal chemothe...

Krajewska(M),Heijink(A M),Bisselink(Y J W ... Oncogene 2013-08-14

...BRCA2 at the Cdk1 phosphorylation site S3291. Taken together, our results indicate that Wee1 inhibition leads to forced ...

Frankenberg-Schwager(Marlis),Gregus(Anke) Int J Radiat Biol 2013-01-07

...BRCA2 mutation carriers.,Primary human fibroblasts from three BRCA1, three BRCA2 mutation carriers, one BRCA2-deficient ...

Marchetti(Claudia),Imperiale(Ludovica),Gas... Expert Opin Investig Drugs 2013-02-13

...BRCA2 (breast cancer 2)-mutated and in sporadic ovarian cancer represents a promising field of investigation. Further st...

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