...BRCA2) are cellular proteins involved in DNA repair. They are normally expressed in the breast, ovaries, prostate, and o...
Germline mutations in BRCA1 and BRCA2 account for ~30 % of inherited breast cancer. BRIP1 and PALB2 are likely genes for...
...BRCA2, and TP53 genes are associated with high risk of breast cancer. Large rearrangements involving these genes are als...
...BRCA2 and CDKN1A interacting protein (BCCIP) and proliferating cell nuclear antigen (PCNA) which are down- and upregulat...
...BRCA2 genetic mutation have an up to 80% lifetime risk of developing breast cancer. It is especially important to unders...
...BRCA2 shows differential allelic expression and we hypothesize that the known variable penetrance of BRCA2 mutations mig...
...BRCA2. A more cost-effective strategy of triaging patients for analysis of a single gene could be adopted if tissue-base...
...BRCA2 (breast cancer 2, early onset) genes responsible for hereditary breast and ovarian cancer are based on limited stu...
...BRCA2 are sensitive to PARG depletion or inhibition. These data raise the exciting possibility that PARG inhibitors may ...
...BRCA2 and TP53 by full DNA sequencing. Of the mutations identified, we examined their likely pathogenicity on the basis ...
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