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The consequences of risk reducing salpingo-oophorectomy: the case for a coord...

Pezaro(Carmel),James(Paul),McKinley(Joanne... Fam Cancer 2013-05-03

...BRCA2 genes have significantly increased lifetime risks of breast and ovarian cancer. To manage both the ovarian and bre...

Mutation screening of RAD51C in high-risk breast and ovarian cancer families.

Lu(Wenping),Wang(Xianshu),Lin(Hongsheng),L... Fam Cancer 2013-05-03

...BRCA2 mutations. The nine exons of the RAD51C gene containing protein coding sequence were screened for mutations in gen...

Limited significance of family history for presence of BRCA1 gene mutation in...

Brozek(Izabela),Ratajska(Magdalena),Piatko... Fam Cancer 2013-05-03

...BRCA2 gene mutation. Most families with detected BRCA1 or BRCA2 gene mutation are qualified for molecular testing on the...

Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carri...

Kotsopoulos(Joanne),Lubinski(Jan),Salmena(... Breast Cancer Res 2013-04-24

...BRCA2 mutation may be helpful for risk assessment and for recommendations regarding prevention. We present an updated an...

Enhanced RAD21 cohesin expression confers poor prognosis in BRCA2 and BRCAX, ...

Yan(Max),Xu(Huiling),Waddell(Nic),Shield-A... Breast Cancer Res 2013-04-24

...BRCA2, for high-fidelity DNA repair by homologous recombination. Although its expression correlates with early relapse a...

Establishment of a PCR analysis method for canine BRCA2.

Yoshikawa(Yasunaga),Morimatsu(Masami),Ochi... BMC Res Notes 2013-02-27

...BRCA2 base sequence and for detecting BRCA2 splicing variants and the BRCA2 ORF consensus sequence are useful for better...

Occupational solvent exposure, genetic variation of DNA repair genes, and the...

Jiao(Jie),Zheng(Tongzhang),Lan(Qing),Chen(... Eur J Cancer Prev 2013-03-01

...BRCA2 (rs144848) for NHL overall (Pfor interaction=0.0042). Our study results suggest that genetic variations in DNA rep...

SET overexpression decreases cell detoxification efficiency: ALDH2 and GSTP1 ...

Almeida(Luciana O),Goto(Renata N),Pestana(... FEBS J 2013-02-04

...BRCA2 recruitment. SET downregulated repair genes ATM, BRCA1 and CHEK2 and upregulated TP53. Cisplatin-induced cell-cycl...

A role for common genomic variants in the assessment of familial breast cance...

Sawyer(Sarah),Mitchell(Gillian),McKinley(J... J Clin Oncol 2013-05-06

...BRCA2 mutation screening as a result of a high risk for hereditary breast cancer. Genotyping of 22 breast cancer-associa...

Mutation analysis of BRCA1, BRCA2, PALB2 and BRD7 in a hospital-based series ...

Pern(Franziska),Bogdanova(Natalia),Schürma... PLoS One 2013-04-05

...BRCA2, PALB2, and BRD7 genes. Microfluidic array PCR and next-generation sequencing was used for BRCA1 and BRCA2 analysi...

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