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Long term follow up of BRCA1 and BRCA2 mutation carriers with unsuspected neo...

Powell(C B),Swisher(E M),Cass(I),McLennan(... Gynecol Oncol 2013-06-11

...BRCA2 mutation carriers. Median and mean age for carcinomas were 50 years and 49.3 respectively, significantly younger t...

Breast cancer and genetics.

Boeri(L),Canzonieri(C),Cagioni(C),Ornati(F... J Ultrasound 2013-02-12

...BRCA2. In 1995 both genes were identified and cloned, and they demonstrated to have only minimal homology. The conclusio...

Inhibition of Poly(ADP-Ribose) Polymerase Enhances Radiochemosensitivity in C...

Shunkwiler(Lauren),Ferris(Gina),Kunos(Char... Int J Mol Sci 2013-02-12

...BRCA2-deficient cancers, very little is known of the PARP inhibition effect upon cancers proficient in DNA double-strand...

Comparative in vitro and in silico analyses of variants in splicing regions o...

Colombo(Mara),De Vecchi(Giovanna),Caleca(L... PLoS One 2013-09-27

...BRCA2 splice sites were characterized by transcripts analysis. These results were used to evaluate the ability of nine b...

Predicting high risk disease using serum and DNA biomarkers.

Vesprini(Danny),Liu(Stanley),Nam(Robert) Curr Opin Urol 2013-09-24

...BRCA2, Phosphatase and tensin homolog, cellular myelocytomatosis oncogene and NKX3.1 may predict for aggressive high gra...

BRCA1 and BRCA2 mutations and female fertility.

Smith(Ken R),Hanson(Heidi A),Hollingshaus(... Curr Opin Obstet Gynecol 2013-12-10

...BRCA2 mutations and their relationship with female fertility.,Eight relevant studies of female fertility, five of which ...

Male breast cancer: risk factors, biology, diagnosis, treatment, and survivor...

Ruddy(K J),Winer(E P) Ann Oncol 2013-11-18

...BRCA2 mutations, age, conditions that alter the estrogen/androgen ratio, and radiation are proven risk factors. Disease ...

Overexpression of full-length centrobin rescues limb malformation but not mal...

Liška(František),Gosele(Claudia),Popova(El... PLoS One 2013-10-22

...BRCA2-interacting protein) truncation at the C-terminus in the hd mutant. Here, we report data from a transgenic rescue ...

Which screening strategy should be offered to women with BRCA1 or BRCA2 mutat...

de Bock(G H),Vermeulen(K M),Jansen(L),Oost... Br J Cancer 2013-07-15

...BRCA2 mutations. The effectiveness and cost-effectiveness of the Dutch, UK and US screening strategies, which involve ma...

BRCA-associated pancreatic cancer: the evolving management.

Leung(Keith),Saif(Muhammad Wasif) JOP 2013-09-12

...BRCA2-associated pancreatic cancer treated with the poly-(ADP-ribose) polymerase (PARP) inhibitor ABT-888 (veliparib). W...

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