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BRCA1/2 mutation screening in high-risk breast/ovarian cancer families and sp...

Berzina(Dace),Nakazawa-Miklasevica(Miki),Z... BMC Med Genet 2013-08-26

...BRCA2 mutations including three novel BRCA2 frameshift mutations and one previously known BRCA2 frameshift mutation and ...

Loss of heterozygosity at 13q13 and 14q32 predicts BRCA2 inactivation in lumi...

Pécuchet(Nicolas),Popova(Tatiana),Manié(El... Int J Cancer 2013-12-09

...BRCA2 inactivation in tumors could help identify patients for whom a genetic test for BRCA2 may be proposed. A series of...

The mammary gland carcinogens: the role of metal compounds and organic solvents.

Mulware(Stephen Juma) Int J Breast Cancer 2013-06-14

...BRCA2 genes have a high risk of developing breast cancer, studies have also shown that significant exposure to certain m...

Polymorphisms in double-strand breaks repair genes are associated with impair...

Ji(Guixiang),Yan(Lifeng),Liu(Wei),Huang(Co... Reproduction 2013-11-25

...BRCA2, RAG1, XRCC5, LIG4, XRCC4 and ATM) in 580 infertility cases and 580 controls from a Chinese population-based case-...

Exome profiling of primary, metastatic and recurrent ovarian carcinomas in a ...

Zhang(Jian),Shi(Yuhao),Lalonde(Emilie),Li(... BMC Cancer 2013-09-16

Ovarian carcinoma is a common, and often deadly, gynecological cancer. Mutations in BRCA1 and BRCA2 genes are present in...

Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of...

Bowman-Colin(Christian),Xia(Bing),Bunting(... Proc Natl Acad Sci U S A 2013-08-06

...BRCA2, and RAD51. To further understand the mechanisms underlying PALB2-mediated DNA repair and tumor suppression functi...

VACTERL-H Association and Fanconi Anemia.

Alter(B P),Rosenberg(P S) Mol Syndromol 2013-05-09

...BRCA2, and 12% FANCD2. Consistent with their genotypes, those with the FA VATER phenotype had a worse prognosis than FA ...

Correlations between BRCA1 defect and environmental factors in the risk of br...

Kang(Hyo Jin),Hong(Young Bin),Yi(Yong Weon... J Toxicol Sci 2013-10-23

...BRCA2 are the most well-known genetic factors that increase risk for breast cancer. Coincidence of those environmental a...

A young woman with bilateral breast cancer: identifying a genetic cause and i...

de Bruin(Monique A),Ford(James M),Kurian(A... J Natl Compr Canc Netw 2013-12-30

...BRCA2, followed, if negative, by consideration of testing for mutations in TP53 (Li-Fraumeni syndrome). Given the specia...

Dealing with the unexpected: consumer responses to direct-access BRCA mutatio...

Francke(Uta),Dijamco(Cheri),Kiefer(Amy K),... PeerJ 2013-07-04

...BRCA2 mutation-positive individuals in the 23andMe customer database who had chosen to view their BRCA reports to partic...

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