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International Cancer of the Pancreas Screening (CAPS) Consortium summit on th...

Canto(Marcia Irene),Harinck(Femme),Hruban(... Gut 2013-04-09

...BRCA2 and hereditary non-polyposis colorectal cancer (HNPCC) mutation carriers with ≥ 1 affected FDR. Consensus was not ...

Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BR...

Chun(Jarin),Buechelmaier(Erika S),Powell(S... Mol Cell Biol 2013-02-21

...BRCA2 and synthetically lethal with Rad52. We conclude that human Rad51 paralogs facilitate BRCA2-Rad51-dependent homolo...

Founder BRCA1/2 mutations in the Europe: implications for hereditary breast-o...

Janavičius(Ramūnas) EPMA J 2013-01-01

Detection of mutations in hereditary breast and ovarian cancer-related BRCA1 and BRCA2 genes is an effective method of c...

Psychosocial factors and uptake of risk-reducing salpingo-oophorectomy in wom...

Meiser(Bettina),Price(Melanie A),Butow(Phy... Fam Cancer 2013-07-18

...BRCA2 mutation carrier or family history including at least one first- or second-degree relative with ovarian or fallopi...

Inherited pancreatic cancer syndromes.

Solomon(Sheila),Das(Siddhartha),Brand(Rand... Cancer J 2013-08-08

...BRCA2, PALB2, ATM, CDKN2A, APC, MLH1, MSH2, MSH6, PMS2, PRSS1, and STK11. Recognition of members of high-risk families i...

Novel cancerization marker, TP53, and its role in distinguishing normal tissu...

Liu(Guo-Yan),Liu(Kun-Hong),Li(Yin),Pan(Cha... World J Surg Oncol 2013-08-02

...BRCA2, FITH, PTCH11 and TP53).,The genetic alterations in TP53 between NTAC and NTAB may provide new insight into the fi...

Genome and transcriptome sequencing in prospective metastatic triple-negative...

Craig(David W),O'Shaughnessy(Joyce A),Kief... Mol Cancer Ther 2013-06-27

...BRCA2, WT1, FGFR1, KRAS, HRAS, ARAF, BRAF, and PGCP. Homozygous deletion of CTNNA1 was detected in 2 of 6 African Americ...

Secondary mutations in BRCA2 associated with clinical resistance to a PARP in...

Barber(Louise J),Sandhu(Shahneen),Chen(Lin... J Pathol 2013-03-19

...BRCA2 secondary mutations in olaparib-resistant metastases. These secondary mutations restored full-length BRCA2 protein...

The risk of primary and contralateral breast cancer after ovarian cancer in B...

Vencken(Peggy M L H),Kriege(Mieke),Hooning... Cancer 2013-04-05

...BRCA2-associated epithelial ovarian cancer (OC).,From the database of the Rotterdam Family Cancer Clinic, patients who h...

Risk of metachronous breast cancer after BRCA mutation-associated ovarian can...

Domchek(Susan M),Jhaveri(Komal),Patil(Suja... Cancer 2013-05-06

...BRCA2). Of these 164 patients, 152 developed OC prior to BRCA testing (median time to testing, 2.4 years [0.01-55 years]...

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