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TP53 BRCA1 CRISPR single-cell cancer

Lin(Wayne T),Beattie(Mary),Chen(Lee-May),O... Cancer 2013-06-11

...BRCA2 (BRCA1/2) are related to an increased lifetime risk of developing breast and ovarian cancer. Although risk-reducin...

Norquist(Barbara M),Pennington(Kathryn P),... Gynecol Oncol 2013-06-24

...BRCA2 (BRCA1/2) mutations. We sought to determine if clinically identified mutation carriers differed in clinical charac...

Mohamed(Faten Zahran),Hussien(Yousry Mosta... Mol Biol Rep 2013-09-13

...BRCA2) are probably responsible for only 40% of the excess familial ovarian cancer risks, suggesting that other suscepti...

Scott(Duncan E),Ehebauer(Matthias T),Pukal... Chembiochem 2013-08-15

...BRCA2 and the recombination enzyme RAD51; it makes use of a screening pipeline of biophysical techniques that we expect ...

Bayraktar(S),Gutierrez-Barrera(A M),Lin(H)... Clin Exp Metastasis 2013-07-19

...BRCA2 carriers and 37 % in non-carriers (P = 0.001). Median follow-up was 2.8 years. BRCA non-carriers and BRCA2 carrier...

Chatterjee(Payel),Choudhary(Gaurav S),Shar... PLoS One 2013-09-23

...BRCA2 that impair homologous recombination. However, since many tumors, including prostate cancer (PCa) rarely have on s...

Sitzmann(James V),Wiebke(Eric A) JAMA Surg 2013-05-23

Risk-reducing bilateral salpingo-oophorectomy (RRBSO) and risk-reducing mastectomy are widely used for BRCA1 and BRCA2 m...

Kamieniak(M M),Muñoz-Repeto(I),Rico(D),Oso... Br J Cancer 2013-07-15

...BRCA2 and 26 non-BRCA1/2) and 15 sporadic tumours in combination with supervised and unsupervised analysis was used to d...

Castro(Elena),Goh(Chee),Olmos(David),Saund... J Clin Oncol 2013-07-01

To analyze the baseline clinicopathologic characteristics of prostate tumors with germline BRCA1 and BRCA2 (BRCA1/2) mut...

Segev(Yakir),Iqbal(Javaid),Lubinski(Jan),G... Gynecol Oncol 2013-08-19

...BRCA2 gene.,We followed 4456 women with a BRCA1 or a BRCA2 mutation for incident cases of endometrial cancer. The incide...

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