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TP53 BRCA1 CRISPR single-cell cancer

Stavropoulou(Alexandra V),Fostira(Florenti... PLoS One 2013-12-27

Germline mutations in the BRCA1 and BRCA2 genes contribute to approximately 18% of hereditary ovarian cancers conferring...

Gaudet(Mia M),Kuchenbaecker(Karoline B),Vi... PLoS Genet 2013-06-13

...BRCA2 mutation carriers. This panel may have clinical utility for women with BRCA2 mutations weighing options for medica...

Couch(Fergus J),Wang(Xianshu),McGuffog(Les... PLoS Genet 2013-06-13

...BRCA2 carriers, suggesting a BRCA1-specific association. The 17q21.31 locus was also associated with ovarian cancer risk...

Buisson(Rémi),Masson(Jean-Yves) Med Sci (Paris) 2013-06-20

...BRCA2 in homologous recombination and genome stability.

Ye(Na),Chen(Chuan-Huizi),Chen(Tiantian),So... J Med Chem 2013-06-11

...BRCA2-deficient cells. Significant potentiation on the cytotoxicity of Temozolomide was also observed. The unique struct...

Băltătescu(G I),Așchie(M),Sârbu(V) Chirurgia (Bucur) 2013-07-31

...BRCA2 gene mutations, for most of the breast and ovarian cancer family. Our case is special because it presents a synchr...

Foulkes(William D),Shuen(Andrew Y) J Pathol 2013-09-13

...BRCA2 remain the most important discoveries in human cancer genetics. Identification of highly penetrant mutations in th...

Srihari(Sriganesh),Ragan(Mark A) Bioinformatics 2013-11-08

...BRCA2 breast tumors showed specific differences even across the two sub-types and revealed novel genes involved therein ...

Lindor(Noralane M),Goldgar(David E),Tavtig... Oncologist 2013-12-31

...BRCA2 VUS, calculated from a multifactorial likelihood model, are explained, and links for looking up specific VUS are p...

Quiles(Francisco),Fernández-Rodríguez(Juan... PLoS One 2013-11-11

...BRCA2 genes are responsible for Hereditary Breast and Ovarian Cancer Syndrome (HBOCS). Genetic testing of these genes is...

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