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Westin(SN),Moore(K),Chon(HS),Pepin(JT),Sal... Gynecol Oncol 2026-03-00

...BRCA2 genes, homologous recombination repair genes, DNA polymerase epsilon and tumour protein 53 [TP53m]) were evaluable...

Matsubayashi(H),Kiyozumi(Y),Ishihara(E),Ha... Jpn J Clin Oncol 2026-05-07

...BRCA2 [10], BRCA1 [6], APC [1], ATM [1], BAP1 [1], CDK4 [1], CDKN2A [1], MSH2 [1], and RAD51C [1]. The 23 patients with ...

Kubota(J),Masuda(S),Makazu(M),Kimura(K),Im... Clin J Gastroenterol 2026-04-00

...BRCA2 variant. After achieving stable disease with 5 months of platinum-based chemotherapy (mFOLFIRINOX), he was transit...

Davies(HR),Black(D),Kvist(A),Sigurjónsdótt... Commun Med (Lond) 2026-02-16

Homologous recombination deficiency (HRD) originating from inactivation of genes like BRCA1/BRCA2 is a targetable abnorm...

Strojnik(K),Blatnik(A),Krajc(M),Novaković(... BJC Rep 2026-02-16

...BRCA2:c.7892 T > C p.(Leu2631Pro), located in the DNA-binding domain, was identified. Extensive family history of cancer...

Patel(R),Kumar(G),Shah(Y),Singh Dahiya(D),... ACG Case Rep J 2026-02-00

...BRCA2, and POLE, with no personal or familial cancer history. This mutational triad suggests convergence of homologous r...

Baskarane(H),Jain(R),Divakar(MK),Seth(A),N... Oncologist 2026-03-06

...BRCA2 (4.2%), and CDK12 (4.2%). Variants of unknown significance (VUS) were detected in 12% (20) of patients. Patients w...

Talafha(MM),Ligon(JA),Henegan(JC),Manucha(... Int J Surg Pathol 2026-08-00

Breast cancer susceptibility gene 2 (BRCA2) and neurofibromatosis type 2 (NF2) are key tumor suppressor genes involved i...

Nusawardhana(A),Nicolae(CM),Moldovan(GL) Nat Commun 2026-02-25

...BRCA2 genes are observed in breast, ovarian, and other cancers. This results in defective homologous recombination DNA r...

Maletta(M),Vicenti(R),Forastiere(C),Di San... J Ovarian Res 2026-02-07

Germline mutations of BRCA1 and BRCA2 may impair DNA repair in the ovarian cortex, leading to increased oocyte apoptosis...