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Ozen(F),Yegin(Z),Sayit(D) J Hum Genet 2026-09-00

...BRCA2, are primarily responsible for inherited breast cancers, while mutations in moderate-risk genes also increase susc...

Wu(J),Stutzman(M),Muriello(M),Lincoln(J),B... Sci Rep 2026-05-23

...BRCA2, FBN1, ATM, PALB2, MYH7, USH2A, and PAH), achieving Leave-One-Out Cross-Validation (LOO-CV) MCC of 0.895-0.989 and...

Allen(S),Rowlands(CF),Garrett(A),Couch(F),... medRxiv 2026-05-17

...BRCA2, PALB2, ATM, CHEK2). A combined LLR was produced for 4,690 missense variants; 927 variants received evidence towar...

Finch(M),Booth(C),Frank(S),Patel(A),Sagoo(... J Oncol Pharm Pract 2026-05-25

...BRCA2 mutations, higher rates of hormone receptor positive HER2-negative cancers and a greater use of neoadjuvant and pl...

Sumii(R),Omote(S),Omote(R),Fujita(I),Toyok... Clin J Gastroenterol 2026-08-00

...BRCA2 and PMS2, alongside a high tumor mutational burden (18.2 mutations/Mb). The elevated tumor mutational burden and t...

Sharma(S),Wong(HY),Johnston(RL),Koufarioti... BMC Cancer 2026-05-25

...BRCA2, CCNE1, CDKN2A, EGFR, KRAS, MDM2, PIK3CA, PTEN, SMARCB1 and TSC2. Candidate co-occurring alterations included co-o...

Imamura(T),Tsuji(Y),Deguchi(K),Okugawa(Y) Hinyokika Kiyo 2026-04-00

...BRCA2 were identified. The diagnosis made was prostate cancer associated with hereditary breast and ovarian cancer syndr...

Zhu(Z),Kitano(T),Morimatsu(M),Orino(K),Yos... Mol Biol Rep 2026-06-30

...BRCA2, a tumor suppressor gene product, promotes HR by directly interacting with RAD51 via eight evolutionarily conserve...

Namey(E),Horton(C),Dudley(B),Carraway(C),K... JAMA Netw Open 2026-06-01

...BRCA2, CHEK2, or PALB2) genes. Statistical analyses were conducted between June 2023 and March 2025. Identification of a...

Allister(BA),Hofmann(W),Lühmann(JL),Sander... NPJ Breast Cancer 2026-06-30

...BRCA2, and other diagnostically consented core genes. We hypothesized that variants in further DNA repair genes, cryptic...