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Familial pancreatic cancer: current status.

Langer(Peter),Slater(Emily),Fendrich(Volke... Expert Opin Med Diagn 2013-03-18

...BRCA2 gene, could be identified in some FPC families. Nevertheless, most experts recommend participation in screening an...

A prospective investigation of predictive and modifiable risk factors for bre...

Guinan(Emer M),Hussey(Juliette),McGarrigle... BMC Cancer 2013-09-16

...BRCA2, the risk of developing breast or ovarian cancer is significantly increased. In recent years there has been increa...

Comprehensive analysis of BRCA1, BRCA2 and TP53 germline mutation and tumor c...

Carraro(Dirce Maria),Koike Folgueira(Maria... PLoS One 2013-08-27

Germline mutations in BRCA1, BRCA2 and TP53 genes have been identified as one of the most important disease-causing issu...

Impairment of BRCA1-related DNA double-strand break repair leads to ovarian a...

Titus(Shiny),Li(Fang),Stobezki(Robert),Aku... Sci Transl Med 2013-07-26

...BRCA2, declines in single mouse and human oocytes. In Brca1-deficient mice, reproductive capacity was impaired, primordi...

Nonfamilial breast cancer subtypes.

Ringnér(Markus),Staaf(Johan),Jönsson(Göran... Methods Mol Biol 2013-07-29

...BRCA2-mutated tumors were significantly correlated to specific subtypes. In this chapter, we will review the current sta...

Systematic detection of pathogenic alu element insertions in NGS-based diagno...

De Brakeleer(Sylvia),De Grève(Jacques),Lis... Hum Mutat 2013-09-30

...BRCA2.

Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumo...

Rytelewski(Mateusz),Ferguson(Peter J),Male... Mol Ther Nucleic Acids 2013-03-14

...BRCA2 mediates homologous recombination repair, and BRCA2 polymorphisms increase cancer risk. However, tumors with BRCA2...

Risk of pancreatic cancer in breast cancer families from the breast cancer fa...

Mocci(Evelina),Milne(Roger L),Méndez-Villa... Cancer Epidemiol Biomarkers... 2013-11-07

...BRCA2 were eligible. Families were divided into four classes: BRCA1, BRCA2, BRCAX with ≥2 breast cancer diagnosed before...

Genetic predisposition syndromes and their management.

Euhus(David M),Robinson(Linda) Surg Clin North Am 2013-04-22

...BRCA2, and TP53, more than a dozen breast cancer susceptibility genes have been identified. Recognizing affected individ...

Miscellaneous syndromes and their management: occult breast cancer, breast ca...

Colfry(Alfred John) Surg Clin North Am 2013-04-22

...BRCA2 mutations, as well as Klinefelter syndrome. Several retrospective trials of surgical therapy in stage IV breast ca...

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