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Therapeutic potential of stem cells expressing suicide genes that selectively...

Yi(Bo-Rim),Choi(Kelvin J),Kim(Seung U),Cho... Int J Oncol 2013-01-23

...BRCA2, p53, PTEN, CHEK2 and ATM. Surgery, chemotherapy, radiotherapy and hormone therapy are used ...

DHPLC/SURVEYOR nuclease: a sensitive, rapid and affordable method to analyze ...

Pilato(Brunella),De Summa(Simona),Danza(Ka... Mol Biotechnol 2013-03-19

Hereditary breast cancer accounts for about 10% of all breast cancers and BRCA1 and BRCA2 genes have been identified as ...

Hereditary ovarian cancer: recent molecular insights and their impact on scre...

Long(Kara C),Kauff(Noah D) Curr Opin Oncol 2013-09-27

...BRCA2 mutations, and the most effective risk-reducing strategies.,Women with BRCA-associated epithelial ovarian cancer r...

Will Chinese ovarian cancer patients benefit from knowing the BRCA2 mutation ...

Liu(Guo-Yan),Zhang(Wei) Chin J Cancer 2013-02-21

In Western countries, the mutation status of the BRCA1 and BRCA2 genes is commonly determined for genetic counseling amo...

A follow-up study on men tested for BRCA1/BRCA2 mutations: impacts and coping...

Shiloh(Shoshana),Dagan(Efrat),Friedman(Iri... Psychooncology 2013-07-31

...BRCA2) among men who undergo genetic testing.,A cross-sectional study compared 51 mutation carriers with 30 men who test...

Inhibition of poly(ADP-ribose) polymerase (PARP) and ataxia telangiectasia mu...

Golla(Radha M),Li(Min),Shen(Yulei),Ji(Ming... Hematol Oncol 2013-02-07

...BRCA2 did not potentiate the cytotoxic effect of treatment with PARPi and topotecan. With loss of function of ATM, other...

Clinical and ethical issues in the diagnosis of hereditary breast cancer (rev...

Ponzone(R),Giai(M),Roagna(R),Sgro(L),Bigli... Int J Oncol 2013-07-04

...BRCA2 has created great interest and expectations among members of families with a positive history for breast/ovarian c...

The impact of prophylactic salpingo-oophorectomy on quality of life and psych...

Finch(Amy),Metcalfe(Kelly A),Chiang(Jaclyn... Psychooncology 2013-05-22

...BRCA2 mutation were invited to participate. Participants completed three questionnaires (SF-12(®) Health Survey, Brief S...

BRCA1 and BRCA2 mutations among familial breast cancer patients from Costa Rica.

Gutiérrez Espeleta(G A),Llacuachaqui(M),Ga... Clin Genet 2013-03-21

...BRCA2 and one in BRCA1) representing 4.5% of the total. Two unrelated patients were found to have a BRCA2 5531delTT muta...

PARP inhibitors: its role in treatment of cancer.

Chen(Alice) Chin J Cancer 2013-03-20

...BRCA2-associated ovarian or breast cancers, and in combination with chemotherapy in triple negative breast cancer. This ...

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