...BRCA2 mutation were invited to participate. Participants completed three questionnaires (SF-12(®) Health Survey, Brief S...
...BRCA2 and one in BRCA1) representing 4.5% of the total. Two unrelated patients were found to have a BRCA2 5531delTT muta...
...BRCA2 did not potentiate the cytotoxic effect of treatment with PARPi and topotecan. With loss of function of ATM, other...
...BRCA2 missense variants have been identified, located throughout the whole gene (Breast Cancer Information Core Database...
...BRCA2 mutations) or Lynch syndrome had been documented, but no action was recorded, and its significance was not appreci...
...BRCA2-associated adnexal cancer. On survival, it might be suggested that BRCA2 carriers have a more favorable outcome th...
...BRCA2 mutations are more frequent than BRCA1 with 20% of cases giving a family history. Risk factors for MBC are poorly ...
...BRCA2 mutation carriers, respectively. We explored associations with ovarian cancer and with breast cancer by tumor hist...
...BRCA2-associated breast cancer, we observed a substantial synergy between the defect in homology-directed DNA repair and...
...BRCA2 promote early-onset cancer with chromosome instability. Here, we report that BRCA2 regulates the spindle assembly ...
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