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[Genetic predisposition for breast cancer: BRCA1 and BRCA2 genes].

Narod(Steven A),Rodríguez(Adriana A) Salud Publica Mex 2012-05-08

...BRCA2 has led to the introduction of genetic tests more complex every time for the evaluation of the hereditary cancer r...

Impact of lifestyle factors on preneoplastic changes in prophylactic oophorecto…

Primas(Helga),Kroiss(Regina),Kalteis(Karin),… Eur J Cancer Prev 2012-05-07

...BRCA2 mutations were included in this retrospective study. All women had undergone genetic counseling and prophylactic s...

Online tool to guide decisions for BRCA1/2 mutation carriers.

Kurian(Allison W),Munoz(Diego F),Rust(Peter)… J Clin Oncol 2012-03-30

Women with BRCA1 or BRCA2 (BRCA1/2) mutations must choose between prophylactic surgeries and screening to manage their h...

BRCA1 and BRCA1 Genes and Inherited Breast and/or Ovarian Cancer: Benefits of G…

Somasundaram(Kumaravel) Indian J Surg Oncol 2012-08-23

The breast cancer associated genes BRCA1 and BRCA2 were discovered in 1994 and 1995 respectively. Since then in addition...

RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break rep…

Galanty(Yaron),Belotserkovskaya(Rimma),Coate… Genes Dev 2012-08-02

...BRCA2 and RAD51 on resected DNA. Consistent with previous data showing that RNF4 targets proteins to the proteasome, we ...

BRCA2 mutations and triple-negative breast cancer.

Meyer(Peter),Landgraf(Katharina),Högel(Bernh… PLoS One 2012-10-29

...BRCA2 was either not analyzed or showed much lower mutation frequencies. Therefore, we screened a group of TNBC patients...

Hyperbaric oxygen treatment for skin flap necrosis after a mastectomy: a case s…

Mermans(Joline F),Tuinder(Stefania),von Meye… Undersea Hyperb Med 2012-06-14

...BRCA2 mutation gene was successfully treated with hyperbaric oxygen therapy.

Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ova…

Jakubowska(A),Rozkrut(D),Antoniou(A),Hamann(… Br J Cancer 2012-08-07

...BRCA2 mutation carriers, and 6211 BRCA1 and 2902 BRCA2 carriers from the Consortium of Investigators of Modifiers of BRC...

Identifying and exploiting defects in the Fanconi anemia/BRCA pathway in oncolo…

Stecklein(Shane R),Jensen(Roy A) Transl Res 2012-10-24

...BRCA2 or components of the Fanconi anemia (FA) complex incite genomic instability and predispose to malignancy. The prod...

Double heterozygosity for mutations in BRCA1 and BRCA2 in German breast cancer …

Heidemann(Simone),Fischer(Christine),Engel(C… Breast Cancer Res Treat 2012-12-13

Double heterozygosity for disease-causing BRCA1 and BRCA2 mutations is a very rare condition in most populations. Here w...

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