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TP53 BRCA1 CRISPR single-cell cancer

Moran(A),O'Hara(C),Khan(S),Shack(L),Woodward… Fam Cancer 2012-11-30

...BRCA2 OCCR region. The present study strengthens the known links between BRCA2 and pancreatic and prostate cancer, but t...

Min(Jaewon),Choi(Eun Shik),Hwang(Kwangwoo),K… J Biol Chem 2012-04-16

...BRCA2 cause gross chromosomal rearrangements. Chromosome structural instability in the absence of BRCA2 is thought to re...

Roy(Rohini),Chun(Jarin),Powell(Simon N) Nat Rev Cancer 2012-02-09

The proteins encoded by the two major breast cancer susceptibility genes, BRCA1 and BRCA2, work in a common pathway of g...

Siaud(Nicolas),Barbera(Maria A),Egashira(Aki… PLoS Genet 2012-03-21

...BRCA2 in HR, we created fusions consisting of various BRCA2 domains and also introduced mutations into these domains to ...

Soslow(Robert A),Han(Guangming),Park(Kay J),… Mod Pathol 2012-07-30

...BRCA2 deficiencies. We selected 43 high-grade serous carcinomas diagnosed at Memorial Sloan-Kettering Cancer Center that...

Okada(Satoko),Tokunaga(Eriko),Kitao(Hiroyuki… Ann Surg Oncol 2012-08-16

...BRCA2 loci, 69 (41.6%) and 52 (31.3%) tumors revealed LOH at BRCA1 and BRCA2 loci, respectively. LOH at BRCA1 LOH or BRC...

Ng(Charlotte K Y),Cooke(Susanna L),Howe(Kevi… J Pathol 2012-04-27

...BRCA2 mutation restoring HR function in the resistant lineage re-stabilized its genome and reduced platinum sensitivity....

Ewald(Ingrid P),Izetti(Patrícia),Vargas(Fern… Hered Cancer Clin Pract 2012-10-02

...BRCA2 genes. In women of Ashkenazi Jewish ascendance, up to 30% of breast and ovarian carcinomas may be attributable to ...

Jonsdottir(Asta Bjork),Stefansson(Olafur And… Eur J Cancer 2012-03-09

...BRCA2 mutation carriers, implying a function for the BRCA2 tumour suppressor in completion of cell division. Here, we ad...

Gilbert(Samuel F),Soliman(Amr S),Karkouri(Me… Breast Dis 2012-06-25

...BRCA2 protein expression status was examined in Egyptian and Moroccan tumors. Androgen receptor CAG repeat length was an...

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