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TP53 BRCA1 CRISPR single-cell cancer

Dick(Michelle G),Versmold(Beatrix),Engel(Chr… Int J Cancer 2012-06-01

...BRCA2 mutations. The DR-4 haplotype 626C-683C [626C > G, Thr209Arg (rs4871857) and 683A > C, Glu228Ala (rs17088993)] has...

Bernholtz(Shiri),Laitman(Yael),Kaufman(Bella… Breast Cancer Res Treat 2012-09-14

BRCA1 and BRCA2 germline mutations substantially increase breast and ovarian cancer risk, yet penetrance is incomplete. ...

Martrat(Griselda),Maxwell(Christopher M),Tom… Breast Cancer Res 2012-05-25

...BRCA2, PALB2, RAD51 and RPA1 that suggest a role for MRG15 in the repair of DNA double-strand breaks. Mrg15-deficient mu...

Miyashita(Hitoshi),Mori(Shiro),Fukumoto(Yuta… Mol Med Rep 2012-10-02

...BRCA2 and DCC was 20.0% (2/10). These observations suggest that transformations in PTHR1 may be involved in carcinogenes...

Srivastava(Niloo),Manvati(Siddharth),Srivast… Breast Cancer Res 2012-05-25

...BRCA2, ATM, MDM2, TP53, CHEK2, CYT-C, BCL-2, H2AFX and P21 were examined using TaqMan gene expression assays. Apoptosis ...

Banerjee(Susana),Kaye(Stan) Curr Oncol Rep 2012-01-05

...BRCA2 genes. Accumulating evidence suggests that PARP inhibitors may have a wider application in the treatment of sporad...

Litton(Jennifer K),Ready(Kaylene),Chen(Huiqi… Cancer 2012-02-28

...BRCA2 mutations, maternal inheritance, paternal inheritance, breast cancer only, and breast cancer-identified and ovaria...

Lu(Huimei),Huang(Yi-Yuan),Mehrotra(Sonam),Dr… PLoS Genet 2012-01-30

...BRCA2- and CDKN1A(p21)-interacting protein that has been implicated in the maintenance of genomic integrity. To understa...

Reeves(Stuart G),Meldrum(Cliff),Groombridge(… Cancer Epidemiol 2012-07-20

...BRCA2 (rs11571653), MSH3 (rs26279), Lig4 (rs1805386), OGG1 (rs1052133), XRCC1 (rs25487), XRCC2 (rs3218536 and rs1799793)...

Clague(Jessica),Wilhoite(Greg),Adamson(Aaron… PLoS One 2012-01-26

BRCA1 and BRCA2 are the most well-known breast cancer susceptibility genes. Additional genes involved in DNA repair have...

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