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Common breast cancer susceptibility alleles are associated with tumour subtypes…

Mulligan(Anna Marie),Couch(Fergus J),Barrowd… Breast Cancer Res 2012-06-25

...BRCA2 carriers. In BRCA2 carriers, SNPs in FGFR2, TOX3, LSP1, SLC4A7/NEK10, 5p12, 2q35, and 1p11.2 were significantly as...

Identification of genetic variation in 11 candidate genes of canine mammary tum…

Borge(K S),Børresen-Dale(A L),Lingaas(F) Vet Comp Oncol 2012-05-09

...BRCA2, BRIP1, CDH1, CHEK2, EGFR, ESR1, HER2, PTEN, STK11 and TP53) and screened for genetic variations. Sixty-four singl...

BRCA2 is a mediator of RAD51- and DMC1-facilitated homologous recombination in …

Seeliger(Katharina),Dukowic-Schulze(Stefanie… New Phytol 2012-05-02

...BRCA2 homologs in Arabidopsis in detail. • As Arabidopsis contains two functional BRCA2 homologs, an Atbrca2 double muta...

Long-term outcomes of BRCA1/BRCA2 testing: risk reduction and surveillance.

Schwartz(Marc D),Isaacs(Claudine),Graves(Kri… Cancer 2012-02-28

...BRCA2 gene testing to benefit public health, mutation carriers must initiate appropriate risk management strategies. The...

Assessing the RNA effect of 26 DNA variants in the BRCA1 and BRCA2 genes.

Menéndez(Mireia),Castellsagué(Joan),Mirete(M… Breast Cancer Res Treat 2012-08-22

...BRCA2 identified approximately 16% of variants of unknown significance (VUS), a significant proportion of which could af...

Identification of the deleterious 2080insA BRCA1 mutation in a male renal cell …

Rashid(Muhammad U),Gull(Sidra),Faisal(Saima)… Fam Cancer 2012-03-02

...BRCA2 genes confer elevated risk of breast and ovarian cancer in females and have a link with variety of cancers other t...

p53- and Bax-mediated apoptosis in injured rat spinal cord.

Kotipatruni(Ramaprasada Rao),Dasari(Venkata … Neurochem Res 2012-01-27

...BRCA2 and H2AX in injured spinal cord tissues. Detection of phospho-H2AX in the nucleus and release of 8-OHdG in cytosol...

Communication of BRCA1 and BRCA2 genetic test results to health care providers …

Ready(K),Arun(B K),Schmeler(K M),Uyei(A),Lit… Fam Cancer 2012-03-02

...BRCA2 genetic test results to health care providers outside of tertiary care settings (termed "outside" health care prov...

Genetic variation in IGF2 and HTRA1 and breast cancer risk among BRCA1 and BRCA…

Neuhausen(Susan L),Brummel(Sean),Ding(Yuan C… Cancer Epidemiol Biomarkers P… 2012-02-01

...BRCA2), HTRA1 for BRCA1 carriers (global P value of 0.005), and MMP3 for BRCA2 carriers (global P = 0.0000007 for BRCA2)...

Variation in breast cancer risk with mutation position, smoking, alcohol, and c…

Lecarpentier(Julie),Noguès(Catherine),Mouret… Breast Cancer Res Treat 2012-03-22

...BRCA2, there was a strong evidence for a region at decreased risk (codons 957-1827) (HR = 0.35, P = 0.005) and for one a...

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