...BRCA2-deficient cells. ASCC3 unwinds DNA to remodel gap-containing fork substrates in vitro, suggesting that ASCC3 promo...
...BRCA2 mutations require individualized counseling for informed decision-making, with benefits weighed against the minima...
...BRCA2 mutations. Other molecular characteristics are important in distinct types of EOC, but the use of matched targeted...
...BRCA2-containing complex subunit 3] isopeptidase complex), a K63-specific deubiquitinase, in hypertensive cardiac remode...
...BRCA2 mutation are frequently advised to undergo risk-reducing bilateral salpingo-oophorectomy (BSO) to lower their sign...
...BRCA2 PVs was comparable between the two regimens (HR 1.11, p = 0.665). Among patients with BRCA2 PVs treated with GnP, ...
...BRCA2 (p.D1451Ifs*12) and a missense mutation in TP53 (p.I195T) were detected, but not GTF2I gene mutations. Conclusions...
...BRCA2 variants, building on the established link between HR deficiency and germline pathogenic variants in these genes. ...
...BRCA2 mutations is exceedingly rare. While BRAF mutations define a distinct KRAS-wildtype subset, and BRCA2 mutations ar...
...BRCA2 gene mutations, whereas their role in tumors with alterations of DNA repair genes other than BRCA1/2 and proteins ...
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