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TP53 BRCA1 CRISPR single-cell cancer

Sidon(L),Ingham(S),Clancy(T),Clayton(R),Clar… Br J Cancer 2012-03-29

...BRCA2 mutation carriers (P=0.045). The 40-59 years category showed the greatest uptake for BRRSO and uptake was signific...

Moran(A),O'Hara(C),Khan(S),Shack(L),Woodward… Fam Cancer 2012-11-30

...BRCA2 OCCR region. The present study strengthens the known links between BRCA2 and pancreatic and prostate cancer, but t...

Hosoya(Noriko),Okajima(Miyuki),Kinomura(Aiko… EMBO Rep 2012-04-24

...BRCA2 and inhibits its role in HR. These findings highlight a new mechanism for chromosomal instability in cancer and ex...

Desrichard(Alexis),Bidet(Yannick),Uhrhammer(… Breast Cancer Res 2012-06-25

...BRCA2 genes are responsible for only a part of hereditary breast cancer (HBC). The origins of "non-BRCA" HBC in families...

Wongsurawat(Thidathip),Jenjaroenpun(Piroon),… Nucleic Acids Res 2012-03-14

...BRCA2, Kras and Ptprd) and neurodegenerative diseases related genes (e.g. ATM, Park2, Ptprd and GLDC) could be prone to ...

Bernholtz(Shiri),Laitman(Yael),Kaufman(Bella… Breast Cancer Res Treat 2012-06-22

BRCA1 and BRCA2 mutation carriers have an increased risk for developing breast (and ovarian) cancer. Non-carriers from w...

Wojdacz(Tomasz K),Thestrup(Britta B),Cold(Sø… Future Oncol 2012-04-30

...BRCA2, APC, RASSF1A and RARβ2 genes in PBLs of a group of women diagnosed with breast cancer, and an age-matched control...

Rockwell(Sara),Liu(Yanfeng),Seow(Helen A),Is… Int J Radiat Biol 2012-04-23

...BRCA2(-/-)) cells and corresponding control cells, and EMT6 tumors in mice assayed using cell survival and tumor growth ...

Maxwell(Christopher A),Benítez(Javier),Gómez… PLoS Biol 2012-03-19

...BRCA2, mutation carriers: n = 7,584, weighted hazard ratio ((w)HR) = 1.09 (95% CI 1.02-1.16), p(trend) = 0.017; and n = ...

Kurian(Allison W),Gong(Gail D),John(Esther M… J Clin Oncol 2012-01-13

Women with germline BRCA1 and BRCA2 mutations have five- to 20-fold increased risks of developing breast and ovarian can...

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