...BRCA2 carriers from 11 centers in the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). Based on the BCAC dat...
...BRCA2. Since there is a link between DNA repair and telomere maintenance mechanisms, we have investigated for the first ...
...BRCA2, potentially requiring different screening guidelines.,Three studies of mutation carriers using annual MRI and mam...
Recurrent mutations constituted nearly three quarters of all BRCA1 mutations and almost half of all BRCA2 mutations iden...
Women with germ line BRCA1 or BRCA2 mutations have a marked increased risk of breast and ovarian cancer compared with th...
...BRCA2, BLM, RAD51, and the MRE11-RAD50-NBS1 complex. Thus, the nature of the intricate coordination of repair processes ...
The breast cancer associated genes BRCA1 and BRCA2 were discovered in 1994 and 1995 respectively. Since then in addition...
...BRCA2. Three recurrent mutations (BRCA1 del exon1-2, BRCA2 4150G>T, and BRCA2 6027del4) account for over 70% of all the ...
...BRCA2, HER2, KRAS and PI3K genes have been associated to this pathology. A genomic variant in the 3' untraslated region ...
...BRCA2 S3291 phosphorylation and MRE11 nuclear foci formation and can be rescued by inhibition of CDK or MRE11 nuclease a...
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