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Clinical profile, BRCA2 expression, and the androgen receptor CAG repeat region…

Gilbert(Samuel F),Soliman(Amr S),Karkouri(Me… Breast Dis 2012-06-25

...BRCA2 protein expression status was examined in Egyptian and Moroccan tumors. Androgen receptor CAG repeat length was an...

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers…

Mavaddat(Nasim),Barrowdale(Daniel),Andrulis(… Cancer Epidemiol Biomarkers P… 2012-04-25

...BRCA2-related (OR for BRCA2 = 3.3, 95% CI: 2.4-4.4; P = 4.4 × 10(-14)), and medullary tumors BRCA1-related (OR for BRCA2...

Description and analysis of genetic variants in French hereditary breast and ov…

Caputo(Sandrine),Benboudjema(Louisa),Sinilni… Nucleic Acids Res 2012-07-05

...BRCA2 databases (http://www.umd.be/BRCA1/ and http://www.umd.be/BRCA2/). These databases have been endorsed by the Frenc...

Improved survival for BRCA2-associated serous ovarian cancer compared with both…

Hyman(David M),Zhou(Qin),Iasonos(Alexia),Gri… Cancer 2012-09-28

...BRCA2-positive patients were alive, respectively. On univariate analysis, age, BRCA2 mutations, debulking status, and ty...

Tetraploidy in BRCA2 breast tumours.

Jonsdottir(Asta Bjork),Stefansson(Olafur And… Eur J Cancer 2012-03-09

...BRCA2 mutation carriers, implying a function for the BRCA2 tumour suppressor in completion of cell division. Here, we ad...

Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients fr…

Koumpis(Chrissovaladis),Dimitrakakis(Constan… Hered Cancer Clin Pract 2012-10-02

Inheritance of a mutation in either BRCA1 or BRCA2 accounts for approximately 5% of all breast cancer cases, but varies ...

Iniparib nonselectively modifies cysteine-containing proteins in tumor cells an…

Liu(Xuesong),Shi(Yan),Maag(David X),Palma(Jo… Clin Cancer Res 2012-08-01

...BRCA2-deficient) cells together with BRCA-proficient MDA-MB-231 and DLD1(+/+) cells. Capan-1 and B16F10 xenograft models...

BRCA mutation testing in determining breast cancer therapy.

Smith(Karen Lisa),Isaacs(Claudine) Cancer J 2012-06-18

...BRCA2 mutations is available at the time of breast cancer diagnosis, BRCA mutation status can be considered when making ...

BRCA2 protein deficiency exaggerates doxorubicin-induced cardiomyocyte apoptosi…

Singh(Krishna K),Shukla(Praphulla C),Quan(Ad… J Biol Chem 2012-04-25

...BRCA2) plays an important role in the repair of DNA damage, and loss of BRCA2 predisposes carriers to breast and ovarian...

Up-regulation of miR-1245 by c-myc targets BRCA2 and impairs DNA repair.

Song(Libing),Dai(Ting),Xie(Yingjun),Wang(Cha… J Mol Cell Biol 2012-08-17

...BRCA2 suppression. These findings uncover a BRCA2 regulatory and signaling pathway in sporadic breast cancer and support...

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