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TP53 BRCA1 CRISPR single-cell cancer

Dick(Michelle G),Versmold(Beatrix),Engel(Chr… Int J Cancer 2012-06-01

...BRCA2 mutations. The DR-4 haplotype 626C-683C [626C > G, Thr209Arg (rs4871857) and 683A > C, Glu228Ala (rs17088993)] has...

Beucher(Andrea),Deckbar(Dorothee),Schumann(E… Radiother Oncol 2012-05-18

...BRCA2+/- fibroblasts.,Both BRCA1+/- and BRCA2+/- cells displayed normal DSB repair in G0 and in G1. In contrast, in G2, ...

Ochiai(K),Yoshikawa(Y),Oonuma(T),Tomioka(Y),… Vet J 2012-03-29

In humans, mutations in the gene for the breast cancer susceptibility protein BRCA2 affect its interactions with the rec...

Caux-Moncoutier(Virginie),Castéra(Laurent),T… Hum Mutat 2012-03-27

...BRCA2 were screened for point mutations and large rearrangements in 1,525 unrelated patients (372 for the validation ste...

De Leeneer(Kim),Hellemans(Jan),De Schrijver(… Hum Mutat 2012-03-27

...BRCA2). The throughput was maximized by increasing uniformity in coverage, obtained by a multiplex approach, which outpe...

Fakkert(Ingrid E),Jansen(Liesbeth),Meijer(Ke… Breast Cancer Res Treat 2012-09-14

Breast cancer screening is offered to BRCA1 and BRCA2 mutation carriers from the age of 25 years because of their increa...

Medová(Michaela),Aebersold(Daniel M),Zimmer(… Int J Cancer 2012-01-26

...BRCA2 complex, which is crucial for error-free HR repair of double strand DNA lesions, presumably via downregulation and...

van der Merwe(N C),Hamel(N),Schneider(S-R),A… Clin Genet 2012-05-07

...BRCA2 exons 10 and 11) revealed an additional four deleterious mutations (BRCA1 c.1504_ 1508del,p.Leu502AlafsX2, BRCA2 c...

Kiely(B E),Friedlander(M L),Milne(R L),Stanh… Fam Cancer 2012-01-10

...BRCA2 mutations, or a family history of breast and ovarian cancer, who underwent RRGS between 1998 and 2008. "Adequate" ...

Faza(Marius Boulos),Kemmler(Stefan),Panse(Vi… Nucleus 2012-06-29

...BRCA2. A recent study from our laboratory has revealed an unexpected non- proteasomal role of Sem1 in mRNA export. We fo...

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