...BRCA2, 77.63 years). When radiation risk was included, a small proportion of diagnosed cancers was attributable to radia...
...BRCA2 proteins and is responsible for facilitating BRCA2-mediated DNA repair. Truncating mutations in the PALB2 gene rep...
BRCA1 and BRCA2 germline mutations are associated with an elevated risk for pancreas adenocarcinoma (PAC). Other BRCA-as...
...BRCA2. BRCA-associated breast and ovarian cancers are hallmarked by genomic instability and high sensitivity to DNA doub...
The true prevalence of BRCA1/BRCA2 (BRCAs) germline mutations in sporadic breast or ovarian cancer (SBC/SOC) in Caucasia...
...BRCA2 are responsible for a substantial proportion of high-risk breast and breast/ovarian cancer families (Collaborative...
...BRCA2 (OR: 1.03; p = 0.788) mutation carriers or in case-case studies in BRCA1/2 carriers (OR: 0.80; p = 0.147). Signifi...
...BRCA2 mutations was undertaken and did not reveal any mutation or unclassified variants. Multiplex ligation-dependent pr...
...BRCA2 tumour suppressor, through the recently reported links between RAD51 paralog deficiencies and tumorigenesis trigge...
...BRCA2 genes through the concept of synthetic lethality. It is suggested that PARP inhibitors cause an increase in DNA si...
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