...BRCA2, mismatch repair genes, or p53 (detailed in Subheading 2.2.). Somatic mutations have been found in sporadic ovaria...
Germline mutations in BRCA1 and BRCA2 explain approximately 25% of all familial breast cancers. Despite intense efforts ...
...BRCA2 play unexpected functions during DNA replication by protecting nascent DNA from Mre11 mediated degradation, which ...
...BRCA2 mutations, respectively. Twenty-six (46%) of 57 BRCA1 carriers achieved a pCR, compared with three (13%) of 23 BRC...
...BRCA2, mismatch repair genes (MMR), and APC genes for breast cancer, Lynch syndrome, and familial adenomatous polyposis ...
...BRCA2 mutation. Less than one third of the polyclonal samples were identified by flow cytometry alone. Cytogenetic chang...
...BRCA2. Additionally, we provide evidence that NF-κB interacts with CtIP-BRCA1 complexes and promotes BRCA1 stabilization...
...BRCA2 is mutually exclusive of amplification of CCNE1 and inactivation of RB1, suggesting distinct alternative causes of...
...BRCA2 genes. Accumulating evidence suggests that PARP inhibitors may have a wider application in the treatment of sporad...
...BRCA2 mutations, maternal inheritance, paternal inheritance, breast cancer only, and breast cancer-identified and ovaria...
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