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Massive parallel amplicon sequencing of the breast cancer genes BRCA1 and BRCA2…

De Leeneer(Kim),Hellemans(Jan),De Schrijver(… Hum Mutat 2012-03-27

...BRCA2). The throughput was maximized by increasing uniformity in coverage, obtained by a multiplex approach, which outpe...

A non-BRCA1/2 hereditary breast cancer sub-group defined by aCGH profiling of g…

Didraga(M A),van Beers(E H),Joosse(S A),Bran… Breast Cancer Res Treat 2012-02-08

Germline mutations in BRCA1 and BRCA2 explain approximately 25% of all familial breast cancers. Despite intense efforts ...

Knockdown of transient receptor potential canonical-1 reduces the proliferation…

Kuang(Chun-yan),Yu(Yang),Wang(Kui),Qian(De-h… Stem Cells Dev 2012-05-22

...Brca2, Camk2b, p21, Ddit3, Inha, Slfn1, Mdm2, Prm1, Bcl2, Mki67, Pmp22, and Ppp2r3a. Finally, we found that a Schlafen 1...

BRCA 1 & 2 mutations in Sudanese secondary school girls with known breast cance…

Elnour(Ahmed M),Elderdery(Abozer Y),Mills(Je… Int J Health Sci (Qassim) 2012-12-26

...BRCA2 mutations among female students with a family history of breast cancer, in secondary schools of Marawi Locality, N...

The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like …

Jönsson(Göran),Staaf(Johan),Vallon-Christers… Cancer Res 2012-12-04

...BRCA2-mutated, and 48 non-BRCA1/2-mutated breast tumors using a custom-designed high-density oligomicroarray covering th...

BRCA1 and BRCA2 unclassified variants and missense polymorphisms in Algerian br…

Cherbal(Farid),Salhi(Nadjet),Bakour(Rabah),A… Dis Markers 2012-09-06

...BRCA2), 31 were new UVs (10 BRCA1 and 21 BRCA2), 7 were rare UVs (4 BRCA1 and 3 BRCA2) and 42 were polymorphic variants ...

Evidence for a link between TNFRSF11A and risk of breast cancer.

Bonifaci(Núria),Palafox(Marta),Pellegrini(Pa… Breast Cancer Res Treat 2012-09-13

...BRCA2) gene. Akin to the results of the Cancer and Genetics Markers of Susceptibility initiative, combined analysis of r...

Law-medicine interfacing: patenting of human genes and mutations.

Fialho(Arsenio M),Chakrabarty(Ananda M) Recent Pat DNA Gene Seq 2012-02-03

...BRCA2 gene patents, in the eligibility of all human and presumably other gene patents. This article argues that while pa...

Brca2, Rad51 and Mre11: performing balancing acts on replication forks.

Costanzo(Vincenzo) DNA Repair (Amst) 2012-01-30

...BRCA2 play unexpected functions during DNA replication by protecting nascent DNA from Mre11 mediated degradation, which ...

Response to neoadjuvant systemic therapy for breast cancer in BRCA mutation car…

Arun(Banu),Bayraktar(Soley),Liu(Diane D),Gut… J Clin Oncol 2012-01-17

...BRCA2 mutations, respectively. Twenty-six (46%) of 57 BRCA1 carriers achieved a pCR, compared with three (13%) of 23 BRC...

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