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TP53 BRCA1 CRISPR single-cell cancer

Couch(Fergus J),Gaudet(Mia M),Antoniou(Anton… Cancer Epidemiol Biomarkers P… 2012-08-28

...BRCA2 mutation carriers, respectively. We explored associations with ovarian cancer and with breast cancer by tumor hist...

Ben Gacem(R),Hachana(M),Ziadi(S),Amara(K),Ks… Cancer Epidemiol 2012-07-20

The aim of this study was to evaluate the contribution of the BRCA1 and BRCA2 promoter methylation in the pathogenesis o...

Blanco(Ana),de la Hoya(Miguel),Balmaña(Judit… Breast Cancer Res Treat 2012-05-22

It has been demonstrated that monoallelic PALB2 (Partner and Localizer of BRCA2) gene mutations predispose to familial b...

Yue(Jingyin),Lu(Huimei),Liu(Jingmei),Berwick… DNA Repair (Amst) 2012-05-18

...BRCA2. Defects of filamin-A impair the repair of DNA double strand breaks (DSBs), resulting in sensitization of cells to...

Kwong(Ava),Wong(Connie H N),Shea(Catherine),… World J Surg 2011-04-14

...BRCA2 mutations. Forty-one tested family members also carried the mutations. Of the females, 85.7% of the index patients...

van der Kolk(Dorina M),de Bock(Geertruida H)… Breast Cancer Res Treat 2011-02-18

...BRCA2 mutation carriers. For ovarian cancer at age 70, it was 58.9% (53.5-64.3%) in BRCA1 and 34.5% (25.0-44.0%) in BRCA...

Møller(Pål),Mæhle(Lovise),Engebretsen(Lars F… Hered Cancer Clin Pract 2011-07-14

Penetrances of BRCA1 and BRCA2 mutations have been derived from retrospective studies, implying the possibility of asce...

Domchek(Susan M),Friebel(Tara M),Garber(Judy… Breast Cancer Res Treat 2011-01-31

...BRCA2 (BRCA1/2) mutation carriers. Occult ovarian/fallopian tube cancers (OOC) detected at the time of RRSO have been re...

Pilato(Brunella),Martinucci(Marianna),Danza(… Breast Cancer Res Treat 2011-05-02

...BRCA2 pathological mutation and polymorphic variants' transmission. Ten and 6 probands carried Mendelian transmitted mut...

Tamboom(Kristiina),Kaasik(Krista),Arsavskaja… Hered Cancer Clin Pract 2011-07-14

The aim of this study was to identify BRCA1 and BRCA2 mutations in the Estonian population. We analyzed genetic data and...

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