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Epigenetic markers of early tumor development.

Dumitrescu(Ramona G) Methods Mol Biol 2012-06-25

...BRCA2, ERα and RARβ2, APC, and RASSF1A have been associated with early stages of mammary gland tumorigenesis and have be...

Multiple pathway-based genetic variations associated with tobacco related multi…

Kotnis(Ashwin),Namkung(Junghyun),Kannan(Sadh… PLoS One 2012-05-29

...BRCA2 Asn³⁷²His. Gene-environment interactions were assessed using MDR analysis. The overall best model by MDR was tobac...

BRCAness profile of sporadic ovarian cancer predicts disease recurrence.

Wysham(Weiya Z),Mhawech-Fauceglia(Paulette),… PLoS One 2012-05-29

...BRCA2 been clearly defined. However, it is clear that defects in HR and other DNA repair pathways are important to the e...

Hereditary ovarian cancer: beyond the usual suspects.

Pennington(Kathryn P),Swisher(Elizabeth M) Gynecol Oncol 2012-03-13

In the past, hereditary ovarian carcinoma was attributed almost entirely to mutations in BRCA1 and BRCA2, with a much sm...

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and B…

Ramus(Susan J),Antoniou(Antonis C),Kuchenbae… Hum Mutat 2012-07-09

Germline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and ovarian cancer. A genome-wide as...

Anthropometric measures and risk of ovarian cancer among BRCA1 and BRCA2 mutati…

McGee(Jacob),Kotsopoulos(Joanne),Lubinski(Ja… Obesity (Silver Spring) 2012-09-04

...BRCA2 mutation has not been evaluated. Thus, we investigated the association between height, weight, changes in body wei...

Familial breast cancer.

Lalloo(F),Evans(D G) Clin Genet 2012-11-13

...BRCA2 and TP53. Moderate risk genes (20-40% risk) including PALB1, BRIP, ATM and CHEK2, and a host of low-risk common al...

PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function.

Ma(Jianglin),Cai(Hong),Wu(Tongde),Sobhian(Bi… Mol Cell Biol 2012-06-29

...BRCA2 and links BRCA1 and BRCA2 in DNA homologous recombination repair and breast cancer suppression. Here, we show that...

Vitamin D receptor gene polymorphisms and male breast cancer risk in Turkish po…

Kizildag(S),Gulsu(E),Bagci(O),Yuksel(E),Cand… J BUON 2012-08-16

...BRCA2) risk factors are already known. One potential target is the vitamin D receptor (VDR). We have investigated whethe...

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes …

Couch(Fergus J),Gaudet(Mia M),Antoniou(Anton… Cancer Epidemiol Biomarkers P… 2012-08-28

...BRCA2 mutation carriers, respectively. We explored associations with ovarian cancer and with breast cancer by tumor hist...

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