...BRCA2 and 55 BRCAX) using a cut-off for positivity at 20% (Shaaban et al. in Clin Cancer Res 14:5228-5235, 2008). BRCA1 ...
...BRCA2 tumor suppressors. This therapeutic approach exploits a synthetic lethal strategy to target the specific DNA repai...
It is not known to what extent participation in a genetic testing program for BRCA1 and BRCA2, which does not include an...
...BRCA2 mutation carriers. At baseline, participants (n = 198) showed low to moderate levels of risk perception, pancreati...
...BRCA2 mutation carriers (additive model: OR, 4.92; 95% CI, 1.11-21.83; P = 0.036; recessive model: OR, 4.88; 95% CI, 1.1...
...BRCA2 functions. This may have implications for the clinical management of BRCA1 and BRCA2 mutation carriers both in bre...
...BRCA2 mutations and TN cancer in BRCA2 mutation carriers in Chinese population are elevated.
...BRCA2, and ATR. These latter pathways highlight the involvement of DNA repair, especially the repair of double strand DN...
...BRCA2 mutation. Information on current alcohol consumption was obtained from a questionnaire administered during the cou...
Heterozygous germ line mutations in the Breast CAncer1 (BRCA1) and BRCA2 genes can lead to a high risk of breast and ova...
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