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Ductal carcinoma in situ in a 25-year-old man presenting with apparent unilater…

Coroneos(C J),Hamm(C) Curr Oncol 2011-07-13

...BRCA2. There is no information on paternal genetic testing.The patient was treated with left subcutaneous mastectomy. Up...

A one-step prescreening for point mutations and large rearrangement in BRCA1 an…

Coulet(Florence),Pires(Filipe),Rouleau(Etien… Genet Test Mol Biomarkers 2011-02-09

...BRCA2. Screening of these two genes is time-consuming and must include exploration of large rearrangements that represen...

The impact of tissue block sampling on the detection of p53 signatures in fallo…

Mehra(Karishma K),Chang(Martin C),Folkins(An… Mod Pathol 2011-04-12

...BRCA2 genes (BRCA+) and controls has been controversial. An initial section and two levels (100-200 μm) from every block...

Variation in rates of uptake of preventive options by Canadian women carrying t…

Metcalfe(Kelly A),Ghadirian(Parviz),Rosen(Ba… Open Med 2011-07-14

Women with a BRCA1 or BRCA2 genetic mutation have several options for cancer prevention, including prophylactic surgery,...

Screening for genomic rearrangements in BRCA1 and BRCA2 genes in Czech high-ris…

Ticha(Ivana),Kleibl(Zdenek),Stribrna(Jana),K… Breast Cancer Res Treat 2011-02-09

...BRCA2 gene is low in many populations. We screened for LGRs in BRCA1 and BRCA2 genes by multiplex ligation-dependent pro...

Germline mutations and polymorphisms in the origins of cancers in women.

Hirshfield(Kim M),Rebbeck(Timothy R),Levine(… J Oncol 2011-07-14

...BRCA2, STK11, PTEN, CHEK2, ATM, BRIP1, PALB2, FGFR2, TGFB1, MDM2, MDM4 as well as several other chromosomal loci. Based ...

The Leu33Pro polymorphism in the ITGB3 gene does not modify BRCA1/2-associated …

Jakubowska(Anna),Rozkrut(Dominik),Antoniou(A… Breast Cancer Res Treat 2011-03-15

...BRCA2 mutation carriers. The ITGB3 Leu33Pro polymorphism does not modify breast or ovarian cancer risk in BRCA1 or BRCA2...

The Emerging Role of PARP Inhibitors in the Treatment of Epithelial Ovarian Can…

Gien(Lilian T),Mackay(Helen J) J Oncol 2011-07-14

...BRCA2. PARP inhibitors potentially represent a major breakthrough for patients with hereditary BRCA-associated cancers. ...

[Pathogenesis of Fanconi anemia: FA-BRCA network -- review].

Li(Yan-Shan),Zhu(Xiao-Fan) Zhongguo Shi Yan Xue Ye Xue Z… 2011-08-24

...BRCA2. The impaired DNA repair due to mutations in FA genes is thought to be one of the main pathogenesis of FA, also cl...

The molecular genetics of breast cancer and targeted therapy.

Suter(Rachel),Marcum(James A) Biologics 2011-07-14

...BRCA2. Although the nature of breast cancer is complex and has frustrated previous attempts at treatment or prevention, ...

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