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Autoantibodies to tailor-made panels of tumor-associated antigens in breast car…

Piura(Ettie),Piura(Benjamin) J Oncol 2011-07-14

...BRCA2, and MUC1, (2) IMP1, p62, Koc, p53, c-MYC, cyclin B1, and survivin, (3) PPIA, PRDX2, FKBP52, HSP-60, and MUC1, (4)...

Poly(ADP-ribose) polymerase-1 inhibition: preclinical and clinical development …

Leung(Mary),Rosen(David),Fields(Scott),Cesan… Mol Med 2011-12-27

...BRCA2 genes have a defect in homologous DNA repair and demonstrate a dependence on alternate DNA repair processes by bas...

Inactivation of Brca2 cooperates with Trp53(R172H) to induce invasive pancreati…

Feldmann(Georg),Karikari(Collins),dal Molin(… Cancer Biol Ther 2011-10-03

...Brca2 deficiency is likely to elucidate valuable diagnostic and therapeutic insights for FPC. Both Brca2 alleles were co...

Splicing and multifactorial analysis of intronic BRCA1 and BRCA2 sequence varia…

Whiley(Phillip J),Guidugli(Lucia),Walker(Log… Hum Mutat 2011-09-19

...BRCA2 sequence alterations of unknown significance. Molecular assays evaluating the effect of intronic variants on nativ...

A mitotic function for the high-mobility group protein HMG20b regulated by its …

Lee(M),Daniels(M J),Garnett(M J),Venkitarama… Oncogene 2011-09-26

...BRCA2 controls mitotic cell division is debated. Several studies by different groups report that BRCA2 deficiency affect...

Identification of BRCA1-deficient ovarian cancers.

Skytte(Anne-Bine),Waldstrøm(Marianne),Rasmus… Acta Obstet Gynecol Scand 2011-07-18

It is believed that 24-40% of ovarian cancers have dysfunction in the BRCA1 or BRCA2 (BRCAness) genes, due to either inh...

FANCD2 but not FANCA promotes cellular resistance to type II topoisomerase pois…

Kachnic(Lisa A),Li(Li),Fournier(Loreen),Ferr… Cancer Lett 2011-05-27

...BRCA2 in the repair of DNA damage caused by the topoisomerase II poison etoposide, we studied the role of FANCD2 in medi...

Prospective study of breast cancer incidence in women with a BRCA1 or BRCA2 mut…

Warner(Ellen),Hill(Kimberley),Causer(Petrina… J Clin Oncol 2011-06-28

...BRCA2 mutation, it is expected that the incidence of advanced-stage breast cancers should be reduced in women undergoing...

Pyrosequencing-based DNA methylation profiling of Fanconi anemia/BRCA pathway g…

Szaumkessel(Marcin),Richter(Julia),Giefing(M… Int J Oncol 2011-10-07

Fanconi anemia (FA) associated genes [FANCA, -B, -C, FANCD1(BRCA2), -D2, -E, -F, -G, -I, -L, -M, FANCN (PALB2), FANCJ(BR...

[Genetic consultation: hereditary cancer risk?].

de Pauw(Antoine),Stoppa-Lyonnet(Dominique) Rev Prat 2011-06-28

...BRCA2 mutations and Lynch syndrome linked to mutations in the DNA mismatch repair genes and associated with high risks o...

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