...BRCA2. Also, the DDR pathway utilizes the kinases ATM and ATR, as well as the phosphorylation of H2AX and MDC1. Together...
...BRCA2 confer susceptibility to different types of cancers such as breast cancer and medulloblastoma. A family with a his...
...BRCA2 genes encoded proteins that are required for efficient HR. In this review, we summarize the strategies of targetin...
...BRCA2 and CD44.,In this case report we show for the first time the methylation analysis of a giant fibroadenoma. The det...
...BRCA2 are recurrently truncated as a result of chromosome rearrangements in prostate cancer. Interestingly, many of the ...
...BRCA2 mutations were associated with a significantly higher primary chemotherapy sensitivity rate (100% for BRCA2-mutate...
...BRCA2 (BRCA1/2) genetic test results have been described in several reports, but the long-terms effects of testing have ...
Germline mutations in either of the two tumor-suppressor genes, BRCA1 and BRCA2, account for a significant proportion of...
...BRCA2 mutation and PrCa among BRCA2 carriers has been shown to be more aggressive, with poorer survival.,To further eval...
...BRCA2 genes. These cancers are characterized by a prolonged sensitivity to platinum agents in spite of presentation at a...
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