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TP53 BRCA1 CRISPR single-cell cancer

Elsakov(Pavel),Kurtinaitis(Juozas),Ostapenko… Hered Cancer Clin Pract 2011-07-14

...BRCA2 as well as by family history showing breast and/or ovary cancer aggregation. In a group of 521 breast cancer patie...

Rajkumar(T),Soumittra(N),Vidubala(E),Sridevi… Hered Cancer Clin Pract 2011-11-10

...BRCA2, hMSH2 and hMLH1. The country's first comprehensive hereditary cancer clinic was established in February 2002. The...

Zuradelli(Monica),Peissel(Bernard),Manoukian… Breast Cancer Res Treat 2011-01-31

Double heterozygosity (DH) for BRCA1 and BRCA2 mutations is a very rare finding, particularly in non-Ashkenazi individua...

Pal(Ranjana),Gochhait(Sailesh),Chattopadhyay… Breast Cancer Res Treat 2011-08-31

...BRCA2 (P = 0.002, OR = 0.2, 95% CI = 0.1-0.6), IFNG (P = 0.0000002, OR = 0.3, 95% CI = 0.2-0.4), and common variant Casp...

Hansen(Thomas V O),Jønson(Lars),Albrechtsen(… Breast Cancer Res Treat 2011-01-31

Germ-line mutations in the tumour suppressor proteins BRCA1 and BRCA2 predispose to breast and ovarian cancer. We have r...

Pilato(Brunella),De Summa(Simona),Danza(Kati… Breast Cancer Res Treat 2011-02-18

Hereditary breast cancer syndrome was firstly associated with BRCA1 and BRCA2 genes the mutations of which confer high r...

Holstege(Henne),van Beers(Erik),Velds(Arno),… BMC Cancer 2011-02-03

...BRCA2-mutated breast cancers we compared aCGH data from 130 mouse Brca1Δ/Δ;p53Δ/Δ, Brca2Δ/Δ;p53Δ/Δ and p53Δ/Δ mammary tu...

Chalmers(Anthony J),Lakshman(Mina),Chan(Norm… Semin Radiat Oncol 2011-01-11

...BRCA2, and NBS1) or defects in genes involved in phosphatase and tensin homolog gene (PTEN) signaling. Defects in specif...

Coulet(Florence),Pires(Filipe),Rouleau(Etien… Genet Test Mol Biomarkers 2011-02-09

...BRCA2. Screening of these two genes is time-consuming and must include exploration of large rearrangements that represen...

Cavallone(Luca),Arcand(Suzanna L),Maugard(Ch… Fam Cancer 2011-03-15

...BRCA2:8765delAG, and BRCA2:E1953X) frequently reported in this founder population; and variants of uncertain clinical si...

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