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[Hereditary breast and ovarian cancers].

Gevensleben(H),Serçe(N),Büttner(R) Pathologe 2011-02-25

...BRCA2 (BRCA: breast cancer). Additional moderate and low penetrance gene variants are currently being analyzed via whole...

Gross genomic alterations and gene expression profiles of high- grade serous ca…

Pradhan(Manohar),Risberg(Björn A),Tropé(Clae… BMC Cancer 2011-02-03

...BRCA2 mutations. The prevalence of aneuploidy and tetraploidy was not statistically different in the three groups with d...

PALB2: a novel inactivating mutation in a Italian breast cancer family.

Balia(Cristina),Sensi(Elisa),Lombardi(Grazia… Fam Cancer 2011-03-15

...BRCA2 germline mutations. The mutational analysis of the PALB2 gene in a index case of an high risk breast cancer family...

Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 det…

Mitra(Anita V),Bancroft(Elizabeth K),Barbach… BJU Int 2011-02-07

To evaluate the role of targeted prostate cancer screening in men with BRCA1 or BRCA2 mutations, an international study,...

Evaluation of established breast cancer risk factors as modifiers of BRCA1 or B…

Moorman(Patricia G),Iversen(Edwin S),Marcom(… Breast Cancer Res Treat 2011-02-09

...BRCA2 mutations using a case-only study design. Breast cancer cases that had been tested for BRCA1 and BRCA2 mutations w...

Penetrance of breast cancer, ovarian cancer and contralateral breast cancer in …

van der Kolk(Dorina M),de Bock(Geertruida H)… Breast Cancer Res Treat 2011-02-18

...BRCA2 mutation carriers. For ovarian cancer at age 70, it was 58.9% (53.5-64.3%) in BRCA1 and 34.5% (25.0-44.0%) in BRCA...

Mutations and polymorphic BRCA variants transmission in breast cancer familial …

Pilato(Brunella),Martinucci(Marianna),Danza(… Breast Cancer Res Treat 2011-05-02

...BRCA2 pathological mutation and polymorphic variants' transmission. Ten and 6 probands carried Mendelian transmitted mut...

Expression of EMSY gene in sporadic ovarian cancer.

Altinisik(Julide),Karateke(Ates),Coksuer(Hak… Mol Biol Rep 2011-03-21

The majority of familial breast and ovarian cancers arise from mutations in the BRCA1 and BRCA2 genes. Amplification at ...

Topoisomerase II-mediated DNA damage is differently repaired during the cell cy…

de Campos-Nebel(Marcelo),Larripa(Irene),Gonz… PLoS One 2011-02-18

...BRCA2- and Rad51C- defective Chinese hamster cells displayed hypersensitivity to Top2 poisons. The analysis by immunoflu...

Genetic profiles distinguish different types of hereditary ovarian cancer.

Domanska(Katarina),Malander(Susanne),Staaf(J… Oncol Rep 2011-01-06

...BRCA2, FOXO1A and RB1. Gains on chromosomes 17 and 19 characterized the HNPCC tumors, but target genes herein are unknow...

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