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TP53 BRCA1 CRISPR single-cell cancer

Bosviel(Rémy),Michard(Emilie),Lavediaux(Guil… Clin Chim Acta 2011-09-30

...BRCA2 methylation but exhibited a trend in the decrease of BRCA2 promoter methylation in peripheral blood DNA of sporadi...

Krawczyk(Przemek M),Eppink(Berina),Essers(Je… Proc Natl Acad Sci U S A 2011-09-29

Defective homologous recombination (HR) DNA repair imposed by BRCA1 or BRCA2 deficiency sensitizes cells to poly (ADP-ri...

Sarkar(Siddik),Mandal(Mahitosh) Breast Cancer (Auckl) 2011-07-14

...BRCA2. But currently, the predictive markers are Estrogen and Progesterone receptors responding to endocrine therapy, an...

Burstein(Harold J) Semin Oncol 2011-06-21

...BRCA2 mutation, will have a better response to targeted therapy and whether targeted agents act synergistically with che...

Ochiai(Kazuhiko),Yoshikawa(Yasunaga),Yoshima… FEBS Lett 2011-09-05

...BRCA2 is essential for recombinational DNA repair. BRCA2 specifically binds to RAD51 via eight BRC repeat motifs and del...

Antoniou(Antonis C),Kartsonaki(Christiana),S… Hum Mol Genet 2011-11-10

...BRCA2 mutation carriers, the involvement of these SNPs to breast cancer susceptibility in mutation carriers is currently...

Hellebrand(Heide),Sutter(Christian),Honisch(… Hum Mutat 2011-09-19

...BRCA2 (PALB2) protein has been linked to Fanconi anemia and breast cancer predisposition. Here we present data of a comp...

Im(Kate M),Kirchhoff(Tomas),Wang(Xianshu),Gr… Hum Genet 2011-12-08

Three founder mutations in BRCA1 and BRCA2 contribute to the risk of hereditary breast and ovarian cancer in Ashkenazi J...

Finch(A),Metcalfe(K A),Chiang(J K),Elit(L),M… Gynecol Oncol 2011-05-16

Prophylactic salpingo-oophorectomy is recommended to women who carry a BRCA1 or BRCA2 mutation to reduce the risks of br...

Carney(Michael E),Basiliere(Michele S),Mates… Hawaii Med J 2011-03-24

...BRCA2 gene sequence testing results, specifically variants of uncertain clinical significance in the BRCA1 and/or BRCA2 ...

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