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Skp2 overexpression is associated with loss of BRCA2 protein in human prostate …

Arbini(Arnaldo A),Greco(Margherita),Yao(Jorg… Am J Pathol 2011-08-26

...BRCA2 protein levels using specific BRCA2 small-interfering RNA. Forced BRCA2 expression in Skp2-overexpressing stable t...

Identification of a novel TP53 cancer susceptibility mutation through whole-gen…

Link(Daniel C),Schuettpelz(Laura G),Shen(Don… JAMA 2011-04-21

...BRCA2 mutations) and therapy-related acute myeloid leukemia (t-AML) and analyzed with the following: whole-genome sequen...

Recent progress in the diagnosis and treatment of ovarian cancer.

Jelovac(Danijela),Armstrong(Deborah K) CA Cancer J Clin 2011-07-01

...BRCA2 gene and those with the Lynch syndrome (hereditary nonpolyposis colorectal cancer) have the highest risk of develo...

Comprehensive prediction of mRNA splicing effects of BRCA1 and BRCA2 variants.

Mucaki(Eliseos J),Ainsworth(Peter),Rogan(Pet… Hum Mutat 2011-10-14

Variants of uncertain significance (VUS) in the BRCA1 and BRCA2 genes potentially affecting coding sequence as well as n...

Breast and ovarian cancer: the forgotten paternal contribution.

McCuaig(Jeanna M),Greenwood(Celia M T),Shuma… J Genet Couns 2011-12-14

...BRCA2 mutations is equally likely through maternal or paternal lineage; however, fewer referrals to cancer genetics clin...

Diabetes and breast cancer among women with BRCA1 and BRCA2 mutations.

Bordeleau(Louise),Lipscombe(Lorraine),Lubins… Cancer 2011-07-28

...BRCA2 mutation.,The authors reviewed the medical histories of 6052 women with a BRCA1 or BRCA2 mutation, half of whom ha...

Assessment of rare BRCA1 and BRCA2 variants of unknown significance using hiera…

Capanu(Marinela),Concannon(Patrick),Haile(Ro… Genet Epidemiol 2011-09-29

...BRCA2. Hierarchical modeling permits leverage of information from observed correlations of characteristics of groups of ...

Germline ATM mutational analysis in BRCA1/BRCA2 negative hereditary breast canc…

Graña(B),Fachal(L),Darder(E),Balmaña(J),Ramó… Breast Cancer Res Treat 2011-10-24

...BRCA2 negative hereditary breast cancer (HBC) cases and 625 matched Spanish controls. For the detection of the 32 ATM mu...

[DNA repair pathways and non-small cell lung cancer: clinical perspectives].

Olaussen(Ken André),Planchard(David),Adam(Ju… Bull Cancer 2011-06-17

...BRCA2 mutations, which are essential proteins in the homologous recombination repair pathway (HR). This phenomenon calle...

Treatment with olaparib in a patient with PTEN-deficient endometrioid endometri…

Forster(Martin D),Dedes(Konstantin J),Sandhu… Nat Rev Clin Oncol 2011-09-01

...BRCA2 mutations, but displayed loss of PTEN, which has been suggested to be another predictive marker for sensitivity to...

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