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The use of family history questionnaires: an examination of genetic risk estima…

Armel(Susan Randall),Hitchman(Kara),Millar(K… J Genet Couns 2011-10-31

...BRCA2 genes and genetic testing eligibility as compared to a responder population of patients who completed a mailed FHQ...

Predictors of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.

Metcalfe(K),Gershman(S),Lynch(H T),Ghadirian… Br J Cancer 2011-06-16

The objective of this study was to estimate the risk of contralateral breast cancer in BRCA1 and BRCA2 carriers; and mea...

Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutat…

Dedes(Konstantin J),Wilkerson(Paul M),Wetter… Cell Cycle 2011-08-31

...BRCA2 loss of function, which harbor deficiency of DNA repair by homologous recombination, inhibition of PARP1 enzymatic...

The relative efficiency of homology-directed repair has distinct effects on pro…

Laulier(Corentin),Cheng(Anita),Stark(Jeremy … Nucleic Acids Res 2011-10-17

...Brca2 and Brca1) are critical for complete chromosome separation during anaphase, while another chromosome break repair ...

[Care of hereditary breast cancer].

Lin(Pei-Chao),Wang(Ruey-Hsia) Hu Li Za Zhi 2011-06-14

...BRCA2 testing. When a client is identified as a gene mutation carrier, nurses should explain to her regarding the implem...

AURKA and BRCA2 expression highly correlate with prognosis of endometrioid ovar…

Yang(Fan),Guo(Xiaoqing),Yang(Gong),Rosen(Dan… Mod Pathol 2011-09-22

...BRCA2 expression. However, the expression of AURKA, BRCA2 and their clinical significance is unknown in endometrioid ova...

Common breast cancer susceptibility alleles and the risk of breast cancer for B…

Antoniou(Antonis C),Beesley(Jonathan),McGuff… Cancer Res 2011-02-10

...BRCA2 carriers. Of the 9 polymorphisms investigated, 7 were associated with breast cancer for BRCA2 carriers (FGFR2, TOX...

Allelic imbalance in BRCA1 and BRCA2 gene expression and familial ovarian cance…

Shen(Jie),Medico(Leo),Zhao(Hua) Cancer Epidemiol Biomarkers P… 2011-06-01

...BRCA2, in the LCLs from familial ovarian cancer patients were found to be significantly increased as compared with famil...

Investigation of DNA damage response and apoptotic gene methylation pattern in …

Pal(Ranjana),Srivastava(Niloo),Chopra(Rupali… Mol Cancer 2011-03-25

...BRCA2 (P=0.007) and hypomethylation of DR4 (P=0.011) in sporadic breast tumor tissues suggested a weak/aberrant activati...

Radiotherapy in the treatment of hereditary breast cancer.

Pierce(Lori J),Haffty(Bruce G) Semin Radiat Oncol 2011-04-19

...BRCA2 genes, the available literature with respect to outcomes related to radiation therapy has inherent limitations wit...

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