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BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and ...

Chen(Xiaowei),Arciero(Cletus A),Wang(Chunr... Cancer Res 2006-07-18

...BARD1 interaction following IR exposure. Importantly, BRCC36 depletion disrupts IR-induced phosphorylation of BRCA1. Imm...

Structure and E3-ligase activity of the Ring-Ring complex of polycomb protein...

Buchwald(Gretel),van der Stoop(Petra),Weic... EMBO J 2006-08-14

...BARD1 complex, but complex formation depends on an N-terminal arm of Ring1b that embraces the Bmi1 Ring-domain. Mutation...

Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients wit...

Karppinen(S-M),Barkardottir(R B),Backenhor... J Med Genet 2006-12-15

BARD1 was originally identified as a BRCA1-interacting protein but has also been described in tumour-suppressive functio...

A mitotic role for BRCA1/BARD1 in tumor suppression?

Clarke(Paul R),Sanderson(Helen S) Cell 2006-12-19

...BARD1 heterodimer participates in mitotic spindle assembly, a process conducted by the GTPase Ran. Loss of this mitotic ...

The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly.

Joukov(Vladimir),Groen(Aaron C),Prokhorova... Cell 2006-12-19

...BARD1 E3 ubiquitin ligase activity. Xenopus BRCA1/BARD1 forms endogenous complexes with three spindle-pole proteins, TPX...

A homologue of the breast cancer-associated gene BARD1 is involved in DNA rep...

Reidt(Wim),Wurz(Rebecca),Wanieck(Kristina)... EMBO J 2006-10-24

...BARD1 homologue. AtBRCA1 and the putative AtBARD1 protein are able to interact with each other as indicated by in vitro ...

A truncated splice variant of human BARD1 that lacks the RING finger and anky...

Tsuzuki(Makiko),Wu(Wenwen),Nishikawa(Hiroy... Cancer Lett 2006-04-28

...BARD1 mRNA variant (BARD1DeltaRIN) isolated from a HeLa cell cDNA library. It is characterized by deletion of exons 2-6 ...

Identification and characterization of missense alterations in the BRCA1 asso...

Sauer(M K),Andrulis(I L) J Med Genet 2006-06-05

...BARD1) was originally identified due to its interaction with the RING domain of BRCA1. BARD1 is required for S phase pro...

BARD1 variants Cys557Ser and Val507Met in breast cancer predisposition.

Vahteristo(Pia),Syrjäkoski(Kirsi),Heikkine... Eur J Hum Genet 2006-09-15

BARD1 (BRCA1-associated RING-domain 1) is a tumor suppressor whose protein product interacts with BRCA1, and in which ra...

Aberrant expression of BARD1 in breast and ovarian cancers with poor prognosi...

Wu(Jian-Yu),Vlastos(Anne-Therese),Pelte(Ma... Int J Cancer 2006-03-02

...BARD1 have been found in inherited and spontaneous breast, ovarian and uterine cancers. BARD1 plays a critical role in D...

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