主页文献库搜索
Real-world data of PARP inhibitors in first-line maintenance for BRCA-mutated...

Yeshala(SK),Panda(SS),Moharana(L),Saju(SV)... J Ovarian Res 2026-02-07

...BRCA2 in 5(10.9%), and non-BRCA HRD + in 11(23.9%). Olaparib was given to 27(58.7%) and Rucaparib to 19(41.3%). At a med...

Variant reclassification in cancer susceptibility genes and an updated varian...

Can(ND),Akcay(IM),Celik(E),Ciftci(C),Unal(... Hum Genomics 2026-02-08

...BRCA2, PALB2, CHEK2, and ATM, while in CRC patients PVs were enriched in MLH1, MUTYH, MSH2, and CHEK2. Notably, CHEK2 wa...

Comprehensive profiling of somatic alterations and HRD characteristics in Chi...

Cui(H),Zhu(M),Ling(B),Zhang(L) Am J Cancer Res None

...BRCA2 NM_000059.3:c.439C>A, were identified in the Chinese population. These findings provide a biological rationale to ...

Durable complete radiographic and biochemical response to olaparib in BRCA2-m...

Ito(F),Kobayashi(K),Hayashi(G),Kamijo(S),F... Urol Case Rep 2026-03-00

...BRCA2-mutated mCRPC who achieved a sustained complete response to olaparib monotherapy. After progression on androgen de...

Altered Estrogen Receptor Signaling Pathway in BRCA2-Deficient Estrogen Recep...

Kawasaki(K),Masuyama(M),Shimoda(M),Seto(I)... Cancer Rep (Hoboken) 2026-04-00

...BRCA2 PV carriers (n = 8) and BRCA2 wild-type patients (n = 59). Furthermore, two BRCA2-deficient ER-positive/HER2-negat...

Astaxanthin Modulates Oxidative Stress, DNA Repair Pathway, and Cell Migratio...

Sevimli(M),Kurt(H),Sevimli(TS) Cell Biochem Biophys 2026-04-25

...BRCA2, RAD50, RAD51, Ku70, Ku80, XRCC1, and XRCC4.ASX inhibited the overexpression of many genes and enhanced the activi...

Hereditary pancreatic cancer: A proposal for surveillance from the Italian As...

Carrara(S),Archibugi(L),Terrin(M),Secchett... Dig Liver Dis 2026-08-00

...BRCA2/ATM/CDKN2A/STK11/PALB2/TP53, as well as mismatch repair genes, confer a substantially higher lifetime risk, while ...

The effect of PARP inhibitor-based targeted therapy on BRCA-mutated ovarian c...

Panjarwanto(DA),Nabila(P),Octavia(L),Indra... Front Oncol None

...BRCA2 genes disrupt homologous recombination repair pathways, creating a therapeutic vulnerability that can be exploited...

Therapy-associated mutagenesis at CTCF binding sites is shaped by chromatin c...

Cheng(KCL),Klein(ZP),Mishra(J),Bahcheli(AT... bioRxiv 2026-04-18

...BRCA2, were associated with increased CBS mutation enrichment following radiotherapy. Together, these findings indicate ...

Shaping CDK4/6 Inhibitor Resistance: BRCA2 Germline Alterations Bias toward R...

Napolitano(F),Hanker(AB) Cancer Res 2026-08-04

...BRCA2 (gBRCA2) alterations predispose tumors toward loss-of-function alterations in RB1, a key mechanism of tumor escape...

上一页 22 23 24 25 26 27 28 29 30 下一页 26 / 共 630

联系地址

山东省济南市章丘区文博路2号

齐鲁师范学院 genelibs生信实验室

山东省济南市高新区舜华路750号

大学科技园北区F座4单元2楼

电话: 0531-88819269

微信公众号

关注微信订阅号,实时查看信息,关注医学生物学动态。


商务邮箱

E-mail: product@genelibs.com