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TP53 BRCA1 CRISPR single-cell cancer

Konecny(Michal),Milly(Miriam),Zavodna(Katari… Breast Cancer Res Treat 2011-05-05

...BRCA2, respectively). Four of the mutations, c.80+4del4, c.1938_1947del10 and c.1166delG in BRCA1 and c.6589delA in BRCA...

Dhillon(Kiranjit K),Swisher(Elizabeth M),Tan… Cancer Sci 2011-06-09

...BRCA2 cause increased risk of developing various cancers, especially breast and ovarian cancers. Tumors that develop in ...

Schneider(Ralph),Slater(Emily P),Sina(Merced… Fam Cancer 2011-10-03

...BRCA2, PALB2, CDKN2a, RNASEL, STK11, NOD2, CHEK2 and PALLD, revealed deleterious causative germline mutations of BRCA2 a...

Yap(Timothy A),Sandhu(Shahneen K),Carden(Cra… CA Cancer J Clin 2011-03-10

...BRCA2 mutation carriers with advanced cancers provide strong evidence for the clinical application of this approach. Eme...

Ramus(Susan J),Kartsonaki(Christiana),Gaythe… J Natl Cancer Inst 2011-02-14

Germline mutations in the BRCA1 and BRCA2 genes are associated with increased risks of breast and ovarian cancers. Altho...

Thomassen(Mads),Pedersen(Inge Søkilde),Vogel… Breast Cancer Res Treat 2011-12-07

...BRCA2 predispose carriers to breast and ovarian cancer. The authors have identified a mutation in BRCA2, 7845+1G>A (c.76...

Drew(Yvette),Mulligan(Evan A),Vong(Wan-Tse),… J Natl Cancer Inst 2011-03-28

...BRCA2 (CAPAN-1 [pancreatic cancer]), one that was heterozygous for BRCA2 (OSEC-1 [ovarian surface epithelial]), and one ...

Mehra(Karishma),Mehrad(Mitra),Ning(Geng),Dra… Front Biosci (Elite Ed) 2011-06-03

...BRCA2 (BCRA+) mutations has unearthed an early malignancy, serous tubal intraepithelial carcinomas (STIC), which has lin...

Rowley(Matthew),Ohashi(Akihiro),Mondal(Gouri… Gastroenterology 2011-05-26

...Brca2 to pancreatic cancer we developed a mouse model of pancreas-specific Brca2 inactivation. Because BRCA2-inactivatin...

Press(Joshua Z),Wurz(Kaitlyn),Norquist(Barba… Neoplasia 2011-03-31

...BRCA2 (WT-FT). WT-FT were compared with histologically normal fallopian tube epithelium from seven women with deleteriou...

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