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TP53 BRCA1 CRISPR single-cell cancer

van der Groep(Petra),van der Wall(Elsken),va… Cell Oncol (Dordr) 2011-07-22

...BRCA2 accounting for about 5% of all breast cancers. Other genes that include CHEK2, PTEN, TP53, ATM, STK11/LKB1, CDH1, ...

Bane(Anita L),Mulligan(Anna Marie),Pinnaduwa… Breast Cancer Res Treat 2011-11-22

...BRCA2. We hypothesized that breast tumors from BRCA2 mutation carriers would be less likely than other familial breast c...

Akbari(Mohammad R),Malekzadeh(Reza),Lepage(P… Hum Genet 2011-07-06

...BRCA2 (also known as Fanconi anemia gene FANCD1) was present in 27 of 746 ESCC cases and in 16 of 1,373 controls (OR = 3...

Yates(Melinda S),Meyer(Larissa A),Deavers(Mi… Cancer Prev Res (Phila) 2011-06-21

...BRCA2 mutation carriers. The majority of the microscopic cancers include cases that were confined to the fallopian tubes...

Allen(Chris),Ashley(Amanda K),Hromas(Robert)… J Mol Cell Biol 2011-06-21

...BRCA2, but retained its role in fork restart. Most cancer therapeutic strategies create DNA replication stress. Thus, it...

Milne(R L),Antoniou(A C) Ann Oncol 2011-03-25

Germline mutations in BRCA1 and BRCA2 confer high risks of female breast and ovarian cancer. However, there is strong ev...

Radice(P),De Summa(S),Caleca(L),Tommasi(S) Ann Oncol 2011-03-25

In the last few years, several studies have focused on the interpretation of unclassified variants (UVs) of BRCA1 and BR...

Mangia(A),Malfettone(A),Simone(G),Darvishian… Ann Oncol 2011-03-25

...BRCA2-deficient cells display genomic instability due to impaired DNA repair and may subsequently be predisposed to mali...

Paradiso(A),Formenti(S) Ann Oncol 2011-03-25

...BRCA2-altered tumours.

Calvert(H),Azzariti(A) Ann Oncol 2011-03-25

...BRCA2 mutations. In vitro PARP inhibitors are highly cytotoxic to cell lines carrying BRCA mutations while only minimall...

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