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TP53 BRCA1 CRISPR single-cell cancer

Rhiem(Kerstin),Foth(Dolores),Wappenschmidt(B… Arch Gynecol Obstet 2011-06-24

...BRCA2 mutation were counseled for preventive options. RRSO was recommended to all mutation carriers at age 40 or 5 years...

Yu(Ke-Da),Yang(Chen),Fan(Lei),Chen(Ao-Xiang)… Breast Cancer Res Treat 2011-08-31

...BRCA2 as well as BRCA1 carriers. A few studies have also investigated the genetic contribution of RAD51 135G>C to the ri...

Badie(Sophie),Escandell(Jose M),Bouwman(Pete… Nat Struct Mol Biol 2011-01-18

...Brca2 accumulated telomere dysfunction-induced foci. Human breast tumors in which BRCA2 was mutated had shorter telomere...

Benito-Aracil(Llúcia),Yagüe-Muñoz(Carmen),Ig… Enferm Clin 2011-04-29

...BRCA2 genes of 157 families. The Sensitivity, Specificity, Positive Predictive Value (PPV) and Negative Predictive Value...

Zhang(Shiyu),Royer(Robert),Li(Song),McLaughl… Gynecol Oncol 2011-06-14

...BRCA2. It is important to have an accurate estimate of the proportion of ovarian cancer patients who carry a mutation an...

Bane(Anita L),Mulligan(Anna Marie),Pinnaduwa… Breast Cancer Res Treat 2011-11-22

...BRCA2. We hypothesized that breast tumors from BRCA2 mutation carriers would be less likely than other familial breast c...

Milne(R L),Antoniou(A C) Ann Oncol 2011-03-25

Germline mutations in BRCA1 and BRCA2 confer high risks of female breast and ovarian cancer. However, there is strong ev...

Radice(P),De Summa(S),Caleca(L),Tommasi(S) Ann Oncol 2011-03-25

In the last few years, several studies have focused on the interpretation of unclassified variants (UVs) of BRCA1 and BR...

Mangia(A),Malfettone(A),Simone(G),Darvishian… Ann Oncol 2011-03-25

...BRCA2-deficient cells display genomic instability due to impaired DNA repair and may subsequently be predisposed to mali...

Paradiso(A),Formenti(S) Ann Oncol 2011-03-25

...BRCA2-altered tumours.

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