...BRCA2- or FANCD2-dependent fork protection is lost. Mechanistically, biochemical reconstitution shows that HELQ is stimu...
...BRCA2, BRIP1, CHEK2, MSH6, PMS2 and ATM. Only a personal history of cancer other than USC was independently associated w...
...BRCA2 pathogenic variants. While risk-reducing salpingo-oophorectomy remains the standard for prevention, conferring red...
...BRCA2 mutations. This retrospective, single-center study included women younger than 50 years with confirmed BRCA1/BRCA2...
...BRCA2, MRE11 and RAD51). Our study demonstrates that the combined intervention of rUCMSC-EVs and chemotherapy drugs can ...
...BRCA2, PALB2, RAD51D, and MSH6 were associated with a 1.3 to twofold abundance of CD163-positive cells. Estrogen recepto...
...BRCA2 mutations and the hormonal imbalance. The management approach, such as surgery, chemotherapy, radiotherapy, and ho...
...BRCA2 depleted cells are highly dependent on TOPBP1-PLK1 complex formation. Altogether, we reveal the molecular details ...
Two saturation genome editing (SGE) studies for BRCA2 using haploid human HAP1 cells and mouse embryonic stem cells, res...
...BRCA2 exceeded BRCA1 in patients ≥70. Moderate-penetrance variants (BRIP1,PALB2) were relatively enriched, while ATM and...
山东省济南市章丘区文博路2号
齐鲁师范学院 genelibs生信实验室
山东省济南市高新区舜华路750号
大学科技园北区F座4单元2楼
电话: 0531-88819269