...BRCA1 (11.5% vs 1%, all q < 0.05), compared to KMT2-wildtype (WT) tumors. Meanwhile, no significant mutational differenc...
...BRCA1 and BRCA2 ( BRCA1/2) genes increase lifetime risk of several cancers including breast and ovarian. Communicating c...
...BRCA1/2 wild-type (BRCA-wt) tumors. The main cohort included patients with HGSC in Alberta, Canada who underwent HRD tes...
Women carrying BRCA1/BRCA2 pathogenic variants face a substantially increased risk of breast cancer and may choose betwe...
...Brca1(L63X/+) rats. Ferric nitrilotriacetate exposure induced dynamic remodeling of proximal tubular epithelium, charact...
...BRCA1 and BRCA2 (BRCA1/2) variant landscape specifically in high-risk, clinically referred populations remains poorly ch...
...BRCA1 and BRCA2, which are essential in maintaining genomic stability. In this study, we describe the lead optimization ...
...BRCA1/2 pathogenic variants (PVs). Unlike Western BRCA1/2 carriers, data regarding this procedure for Chinese healthy wo...
...BRCA1/2 wild-type MIA PaCa-2 and BxPC-3 cells, whereas the effect was minimal in BRCA2-deficient Capan-1 cells. Compared...
...BRCA1/2 mutations and/or a Genomic Scar Score (GSS) ≥45. Clinicopathological correlations and survival outcomes were eva...
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