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Feline mammary basal-like adenocarcinomas: a potential model for human triple-n…

Wiese(David A),Thaiwong(Tuddow),Yuzbasiyan-G… BMC Cancer 2014-06-23

...BRCA1 and BRCA2 genes were analyzed in triple negative, basal-like FMAs.,IHC for ER, PR and HER2 identified 14 of the 24...

Protein expression and methylation of DNA repair genes hMLH1, hMSH2, MGMT and B…

Alkam(Yimit),Mitomi(Hiroyuki),Nakai(Katsuya)… Histopathology 2014-06-09

...BRCA1 methylation or mutation. We comparatively evaluated alterations of DNA repair proteins and p53 between BLBC and no...

[Multiple primary malignancies in BRCA1 mutation carriers--two clinical cases].

Badora(Agnieszka),Kaleta(Beata),Nowara(Elzbi… Ginekol Pol 2014-01-09

Mutations of BRCA1 and BRCA2 genes account for the majority of hereditary breast and ovarian cancers. So far; risk-reduc...

Molecular pathways: how can BRCA-mutated tumors become resistant to PARP inhibi…

Bouwman(Peter),Jonkers(Jos) Clin Cancer Res 2014-10-06

...BRCA1- and BRCA2-associated cancers. However, not all patients respond equally well and tumors may eventually become res...

Epigenetic inactivation of the BRCA1 interactor SRBC and resistance to oxalipla…

Moutinho(Catia),Martinez-Cardús(Anna),Santos… J Natl Cancer Inst 2014-02-28

...BRCA1 interactor SRBC gene. SRBC overexpression or depletion gives rise to sensitivity or resistance to oxaliplatin, res...

A rapid genetic counselling and testing in newly diagnosed breast cancer is ass…

Cortesi(L),Razzaboni(E),Toss(A),De Matteis(E… Ann Oncol 2014-08-11

...BRCA1/2 mutation carriers by up to 95%, but the Italian attitude towards this procedure is reluctant.,This is an observa...

Establishing the origin of metastatic deposits in the setting of multiple prima…

De Mattos-Arruda(Leticia),Bidard(Francois-Cl… Mol Oncol 2014-09-19

...BRCA1 germline mutations, all lesions harbored somatic loss of the BRCA1 wild-type allele and TP53 somatic mutations. Th...

Molecular adaptation of telomere associated genes in mammals.

Morgan(Claire C),Mc Cartney(Ann M),Donoghue(… BMC Evol Biol 2014-12-15

...BRCA1.,These results demonstrate the multifarious selective pressures acting across the mammal phylogeny driving lineage...

Expression of estrogen-related gene markers in breast cancer tissue predicts ar…

Moy(Irene),Lin(Zhihong),Rademaker(Alfred W),… PLoS One 2014-08-20

...BRCA1 and PR-were measured by real-time PCR. Tumor protein and mRNA levels were compared with breast cancer progression ...

Preventing breast and ovarian cancers in high-risk BRCA1 and BRCA2 mutation car…

Collins(Ian M),Milne(Roger L),Weideman(Prue … Med J Aust 2014-01-13

...BRCA1 and BRCA2 mutation carriers.,Prospective follow-up of female carriers of BRCA1 or BRCA2 mutations who had no perso...

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